Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22461930 | 1.00 | FDPS (0.36) | FDPSKDM4ENPC1CYP1A2CYP2D6 | |
| SCHEMBL20833228 | 0.94 | KDM4E (0.41) | FDPSKDM4ENPC1CYP1A2CYP2D6 | |
| SCHEMBL20833322 | 0.94 | KDM4E (0.41) | FDPSKDM4ENPC1CYP1A2CYP2D6 | |
| SCHEMBL7356572 | 0.82 | KDM4E (0.35) | FDPSKDM4ENPC1CYP1A2CYP2D6 | |
| SCHEMBL9340449 | 0.82 | CCR2 (0.35) | FDPSKDM4ENPC1CYP1A2CYP2D6 | |
| SCHEMBL24317161 | 0.79 | CCR2 (0.32) | FDPSKDM4ENPC1CYP1A2CYP2D6 | |
| SCHEMBL22570154 | 0.79 | CCR2 (0.32) | FDPSKDM4ENPC1CYP1A2CYP2D6 | |
| SCHEMBL13930833 | 0.79 | CCR2 (0.32) | FDPSKDM4ENPC1CYP1A2CYP2D6 | |
| SCHEMBL17307730 | 0.79 | CCR2 (0.32) | FDPSKDM4ENPC1CYP1A2CYP2D6 | |
| SCHEMBL16448784 | 0.79 | KDM4E (0.40) | FDPSKDM4ENPC1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177797-A9 | NOVEL USE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-15 | — | — | EP | disclosed |
| EP-1177797-A1 | NOVEL USE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-02-06 | — | — | EP | disclosed |