SCHEMBL749897

SCHEMBL749897

CCOC(C)(OCC)[SiH2]NC1CCCCC1

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.34
LMNA P02545 2/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
TSHR P16473 1/20 0.33
HTT P42858 1/20 0.33
THRB P10828 1/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
EPHX2 P34913 1/20 0.31
EPHX1 P07099 2/20 0.30
ALDH1A1 P00352 2/20 0.30
ALOX12 P18054 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27687540 0.79 ALDH1A1 (0.33) NPSR1GAAHTTEPHX2EPHX1
SCHEMBL16197509 0.75 NPSR1 (0.33) NPSR1GAAHTTTHRBATM
SCHEMBL16192534 0.70 KDM4E (0.36) NPSR1ALDH1A1
SCHEMBL18991269 0.65 ALDH1A1 (0.39) NPSR1EPHX1ALDH1A1HSD17B10
SCHEMBL1455086 0.63 KDM4E (0.34) NPSR1GAAHTTTHRBATM
SCHEMBL10884989 0.63 THRB (0.36) NPSR1THRBATML3MBTL1MMP1
SCHEMBL23084777 0.63 ALDH1A1 (0.38) NPSR1EPHX2EPHX1ALDH1A1HSD17B10
SCHEMBL467903 0.63 KDM4E (0.36) NPSR1GAATSHRHTTTHRB
SCHEMBL16416558 0.63 THRB (0.33) NPSR1THRBATML3MBTL1MMP1
SCHEMBL1356812 0.61 CA1 (0.35) NPSR1LMNATHRBATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118591589-A Curable composition 株式会社钟化 2024-09-03 CN disclosed
CN-116769296-A Curable composition 株式会社钟化 2023-09-19 CN disclosed
CN-113795547-B Curable composition and cured product 株式会社钟化 2023-06-23 CN disclosed
CN-113795547-A Curable composition and cured product 株式会社钟化 2021-12-14 CN disclosed
WO-2020196228-A1 CURABLE COMPOSITION AND CURED PRODUCT 株式会社カネカ 2020-10-01 WO disclosed
EP-2430075-A2 MOISTURE CURABLE POLYDISULFIDES Henkel Corporation (US) 2012-03-21 EP disclosed
WO-2010126920-A2 MOISTURE CURABLE POLYDISULFIDES HENKEL CORPORATION (US) 2010-11-04 WO disclosed