Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | ATP4A | P20648 | 2/20 | 0.48 |
| ▸ | ATP4B | P51164 | 2/20 | 0.48 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.43 |
| ▸ | GUCY1B2 | O75343 | 3/20 | 0.42 |
| ▸ | GUCY1A2 | P33402 | 3/20 | 0.42 |
| ▸ | GUCY1A1 | Q02108 | 3/20 | 0.42 |
| ▸ | GUCY1B1 | Q02153 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8803895 | 0.85 | CYP3A4 (0.83) | CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL8137658 | 0.83 | CYP1A2 (0.55) | CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL8805202 | 0.80 | CYP1A2 (0.53) | CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL7497880 | 0.80 | CYP3A4 (0.50) | CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL7836196 | 0.79 | ATP4A (0.67) | CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL7509329 | 0.79 | CYP3A4 (0.56) | CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL7505990 | 0.79 | CYP1A2 (0.51) | CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9686421 | 0.79 | CYP3A4 (0.58) | CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL7839635 | 0.77 | CYP1A2 (0.49) | CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL7499698 | 0.77 | CYP1A2 (0.49) | CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773946-B1 | IMIDAZOPYRIDINE-AZOLIDINONES | BYK GULDEN LOMBERG CHEM FAB (DE) | 2002-03-27 | — | — | EP | disclosed |
| US-6124313-A | ACTIVE DRUG FOR TREATING GASTRO-INTESTINAL AILMENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2000-09-26 | — | — | US | disclosed |
| US-5665730-A | GASTROINTESTINAL DISORDERS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1997-09-09 | — | — | US | disclosed |
| EP-0773945-A1 | ACYL IMIDAZOPYRIDINES | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996003404-A1 | ACYL IMIDAZOPYRIDINES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1996-02-08 | — | — | WO | disclosed |