Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7499156 | 1.00 | NOS1 (0.36) | NOS1PDE4B | |
| SCHEMBL7499635 | 0.74 | NOS1 (0.58) | NOS1 | |
| SCHEMBL7501072 | 0.74 | NOS1 (0.44) | NOS1PDE4B | |
| SCHEMBL3285131 | 0.65 | ELANE (0.38) | NOS1PDE4B | |
| SCHEMBL14936429 | 0.65 | ELANE (0.38) | NOS1PDE4B | |
| SCHEMBL128493 | 0.64 | — | — | |
| SCHEMBL8215896 | 0.64 | NOS1 (0.57) | NOS1 | |
| Hydrochloric Acid SCHEMBL11561704 | 0.62 | — | — | |
| SCHEMBL1021803 | 0.61 | NOS1 (0.52) | NOS1PDE4B | |
| SCHEMBL14385408 | 0.61 | NOS1 (0.52) | NOS1PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0859607-B1 | GUANIDINO PROTEASE INHIBITORS | DIMENSIONAL PHARM INC (US) | 2002-12-18 | — | — | EP | disclosed |
| EP-0859607-A4 | GUANIDINO PROTEASE INHIBITORS | DIMENSIONAL PHARM INC (US) | 1999-05-06 | — | — | EP | disclosed |
| EP-0859607-A1 | GUANIDINO PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1998-08-26 | — | — | EP | disclosed |
| US-5792769-A | POTENT ANTICOAGULANT, ANTIINFLAMMATORY AGENT; TREATMENT/PROPHYLAXIS OF RESPIRATORY SYSTEM DISORDERS, VASCULAR SYSTEM DISORDERS, ANTITUMOR AGENTS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1998-08-11 | — | — | US | disclosed |
| WO-1997011693-A1 | GUANIDINO PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1997-04-03 | — | — | WO | disclosed |