SCHEMBL8215896

SCHEMBL8215896

CCCC/N=C(\NC(=O)O)n1cccn1

nearest known ligand 0.57

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 6/20 0.57
ELANE P08246 1/20 0.35
SCN5A Q14524 1/20 0.35
SCN2A Q99250 1/20 0.35
TLR8 Q9NR97 1/20 0.32
TLR7 Q9NYK1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2703386 0.78 NOS1 (0.50) NOS1
SCHEMBL3285131 0.74 ELANE (0.38) NOS1ELANE
Hydrochloric Acid SCHEMBL6510363 0.72 NOS1 (0.97) NOS1
SCHEMBL8196529 0.69 NOS1 (0.39) NOS1ELANE
SCHEMBL9012507 0.69 NOS1 (0.43) NOS1
SCHEMBL2127300 0.69 ELANE (0.35) NOS1ELANE
SCHEMBL17560519 0.69 ELANE (0.35) NOS1ELANE
SCHEMBL8201443 0.69 SMN1; SMN2 (0.37) NOS1ELANE
SCHEMBL2343819 0.69 ELANE (0.35) NOS1ELANE
Hydrochloric Acid SCHEMBL6504407 0.68 NOS1 (0.97) NOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000078723-A1 PROCESS FOR THE PREPARATION OF BUTOXYCARBONYLIMINO COMPOUNDS AND INTERMEDIATES THEREFOR GLAXO GROUP LIMITED (GB) 2000-12-28 WO disclosed