Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 6/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.56 |
| ▸ | RXRA | P19793 | 4/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7499394 | 0.88 | PDE4B (0.50) | PDE4BPDE4DRXRANR4A2TSHR | |
| SCHEMBL7498883 | 0.84 | SMN1; SMN2 (0.42) | PDE4BPDE4DRXRANR4A2TSHR | |
| SCHEMBL7504132 | 0.80 | TSHR (0.41) | PDE4BPDE4DRXRANR4A2TSHR | |
| SCHEMBL7503357 | 0.80 | RXRA (0.53) | PDE4BPDE4DRXRANR4A2TSHR | |
| SCHEMBL7212190 | 0.77 | SMN1; SMN2 (0.46) | PDE4BALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL7507585 | 0.77 | ALDH1A1 (0.45) | PDE4BALDH1A1LMNASMN1; SMN2NPC1 | |
| SCHEMBL7498343 | 0.77 | NPSR1 (0.46) | PDE4DRXRANR4A2TSHRKDM4E | |
| SCHEMBL7504573 | 0.77 | PDE4B (0.53) | PDE4BALDH1A1LMNATP53 | |
| SCHEMBL7505001 | 0.77 | MEN1 (0.53) | RXRANPC1ADORA3RAB9A | |
| SCHEMBL7502926 | 0.76 | SMN1; SMN2 (0.40) | PDE4BALDH1A1LMNASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826673-B1 | ACETAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO (JP) | 2002-11-20 | — | — | EP | disclosed |
| US-5972946-A | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0826673-A1 | ACETAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1998-03-04 | — | — | EP | disclosed |