Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | CDC7 | O00311 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4339718 | 0.83 | CDC7 (0.57) | ALDH1A1HSD17B10BRD4KDM4EMAPT | |
| SCHEMBL7997890 | 0.80 | ALDH1A1 (0.56) | ALDH1A1HSD17B10TSHRBRD4KDM4E | |
| SCHEMBL1894350 | 0.78 | ALDH1A1 (0.50) | ALDH1A1HSD17B10TSHRKDM4EMAPT | |
| SCHEMBL13446707 | 0.77 | BRD4 (0.52) | ALDH1A1HSD17B10TSHRBRD4KDM4E | |
| SCHEMBL4891722 | 0.77 | ALDH1A1 (0.53) | ALDH1A1HSD17B10KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL6536223 | 0.77 | TSHR (0.62) | ALOX5ALDH1A1HSD17B10ERN1TSHR | |
| SCHEMBL7497896 | 0.77 | ALDH1A1 (0.57) | ALDH1A1HSD17B10KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL873499 | 0.76 | TSHR (0.71) | ALDH1A1HSD17B10ERN1TSHRKDM4E | |
| SCHEMBL29678391 | 0.76 | TSHR (0.71) | ALDH1A1HSD17B10ERN1TSHRKDM4E | |
| SCHEMBL18342044 | 0.75 | MEN1 (0.55) | ALDH1A1HSD17B10TSHRKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0836605-B1 | PYRROLOPYRIMIDINES AND PROCESSES FOR THE PREPARATION THEREOF | NOVARTIS AG (CH) | 2002-02-06 | — | — | EP | disclosed |
| US-6140332-A | Pyrrolopyrimidines and processes for the preparation thereof | NOVARTIS AG (CH) | 2000-10-31 | — | — | US | disclosed |