SCHEMBL4339718

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2199976	0.85	BRD4 (0.43)	CDC7BRD4
	SCHEMBL4347006	0.85	BRD4 (0.48)	CDC7BRD4PARP1MEN1MAPT
	SCHEMBL13446707	0.85	BRD4 (0.52)	CDC7BRD4KDM4EMEN1ALDH1A1
	SCHEMBL13630074	0.84	BRD4 (0.56)	CDC7BRD4PARP1KDM4EALDH1A1
	SCHEMBL13630194	0.83	BRD4 (0.44)	CDC7BRD4MAPK8KDM4EALDH1A1
	SCHEMBL4344675	0.83	BRD4 (0.46)	CDC7BRD4MPOMEN1ALDH1A1
	SCHEMBL13446626	0.83	BRD4 (0.50)	CDC7BRD4KDM4EMEN1ALDH1A1
	SCHEMBL7499322	0.83	ALOX5 (0.48)	CDC7BRD4MPOKDM4EMEN1
	SCHEMBL2196927	0.82	CDC7 (0.54)	CDC7BRD4PARP1CHUKINSR
	SCHEMBL4343620	0.82	JAK2 (0.49)	CDC7BRD4MAPK8KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.