Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ASPH | Q12797 | 1/20 | 0.35 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.35 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31535408 | 0.85 | ALDH1A1 (0.47) | MAPTALDH1A1KMT2AKDM4EASPH | |
| SCHEMBL2639019 | 0.85 | ALDH1A1 (0.37) | MAPTALDH1A1MEN1KMT2ATEAD4 | |
| SCHEMBL31535331 | 0.83 | SOS1 (0.40) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL7506761 | 0.80 | KEAP1 (0.43) | MAPTALDH1A1MEN1KMT2ATEAD4 | |
| SCHEMBL592060 | 0.79 | HSD17B10 (0.50) | MAPTALDH1A1KDM4EASPHKDM8 | |
| SCHEMBL14915656 | 0.77 | KDM4E (0.35) | ALDH1A1KDM4EASPHKDM8TAS2R14 | |
| SCHEMBL7012967 | 0.75 | KEAP1 (0.34) | MAPTALDH1A1MEN1KMT2ATEAD4 | |
| SCHEMBL25853113 | 0.75 | HSD17B10 (0.49) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL31535254 | 0.75 | HSD17B10 (0.49) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL7506686 | 0.75 | KMT2A (0.39) | MAPTALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882725-B1 | QUINOLONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2002-12-18 | — | — | EP | disclosed |
| US-6025370-A | METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS | TOYAMA CHEMICAL CO., LTD. (JP) | 2000-02-15 | — | — | US | disclosed |
| EP-0882725-A1 | QUINOLONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 1998-12-09 | — | — | EP | disclosed |