SCHEMBL7499424

SCHEMBL7499424

CC(C)=NNC(=S)Nc1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 8/20 0.60
MAPT P10636 6/20 0.60
ALDH1A1 P00352 5/20 0.60
SMN1; SMN2 Q16637 3/20 0.60
TAS2R38 P59533 2/20 0.59
CYP3A4 P08684 2/20 0.59
HSD17B10 Q99714 1/20 0.59
KMT2A Q03164 5/20 0.55
MEN1 O00255 2/20 0.55
NPC1 O15118 2/20 0.55
RAB9A P51151 1/20 0.55
NOX1 Q9Y5S8 1/20 0.55
ALOX12 P18054 2/20 0.55
CYP1A2 P05177 2/20 0.55
CYP2C9 P11712 2/20 0.55
CYP2C19 P33261 2/20 0.55
TDP1 Q9NUW8 1/20 0.55
EPHX1 P07099 1/20 0.55
LMNA P02545 2/20 0.52
CCR6 P51684 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8223150 0.89 GAA (0.60) GAAMAPTALDH1A1SMN1; SMN2TAS2R38
SCHEMBL20395018 0.84 GAA (0.55) GAAMAPTALDH1A1SMN1; SMN2TAS2R38
SCHEMBL4097497 0.83 EPHX1 (0.54) GAAMAPTALDH1A1SMN1; SMN2TAS2R38
SCHEMBL12727673 0.82 GAA (0.57) GAAMAPTALDH1A1SMN1; SMN2TAS2R38
SCHEMBL8210672 0.82 GAA (0.58) GAAMAPTALDH1A1SMN1; SMN2TAS2R38
SCHEMBL1641570 0.82 GAA (0.57) GAAMAPTALDH1A1SMN1; SMN2TAS2R38
SCHEMBL12727671 0.81 GAA (0.53) GAAMAPTALDH1A1SMN1; SMN2TAS2R38
SCHEMBL9321789 0.76 HSP90AA1 (0.77) MAPTALDH1A1SMN1; SMN2KMT2ANPC1
SCHEMBL22056641 0.76 HSP90AA1 (0.77) MAPTALDH1A1SMN1; SMN2KMT2ANPC1
SCHEMBL132620 0.76 ALDH1A1 (1.00) GAAMAPTALDH1A1TAS2R38CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111705312-A Chemical tin plating solution and preparation method and application thereof 信丰正天伟电子科技有限公司 2020-09-25 CN disclosed
EP-0638075-B1 THIAZOLE OR IMIDAZOLE DERIVATIVES AS MAILLARD REACTION INHIBITORS OTSUKA PHARMA CO LTD (JP) 2002-01-16 EP disclosed
CN-1067992-C Substituted thiazolidine derivatives and pharmaceutical compositions containing them and use thereof OTSUKA PHARMA CO LTD (JP) 2001-07-04 CN disclosed
CN-1184105-A Substituted thiazolidine derivatives and pharmaceutical compositions containing them and use thereof OTSUKA PHARMA CO LTD (JP) 1998-06-10 CN disclosed
CN-1037842-C Substituted thiazolidine derivatives, pharmaceutical compositions and uses thereof OTSUKA PHARMA CO LTD (JP) 1998-03-25 CN disclosed
US-5677322-A THERAPY FOR AGING, DIABETES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1997-10-14 US disclosed
CN-1106982-A Maillard reaction inhibitor OTSUKA PHARMA CO LTD (JP) 1995-08-16 CN disclosed
EP-0638075-A1 THIAZOLE OR IMIDAZOLE DERIVATIVES AS MAILLARD REACTION INHIBITORS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1995-02-15 EP disclosed
WO-1994019335-A1 THIAZOLE OR IMIDAZOLE DERIVATIVES AS MAILLARD REACTION INHIBITORS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1994-09-01 WO disclosed