Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 9/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | TAS2R38 | P59533 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8223150 | 0.93 | GAA (0.60) | GAATDP1NPSR1MAPTSMN1; SMN2 | |
| SCHEMBL12727664 | 0.91 | GAA (0.50) | GAATDP1NPSR1MAPTSMN1; SMN2 | |
| SCHEMBL12026319 | 0.87 | GAA (0.49) | GAATDP1NPSR1MAPTSMN1; SMN2 | |
| SCHEMBL12727671 | 0.85 | GAA (0.53) | GAATDP1NPSR1MAPTSMN1; SMN2 | |
| SCHEMBL12045486 | 0.84 | GAA (0.44) | GAATDP1NPSR1MAPTSMN1; SMN2 | |
| SCHEMBL12727673 | 0.83 | GAA (0.57) | GAATDP1NPSR1MAPTSMN1; SMN2 | |
| SCHEMBL1641570 | 0.83 | GAA (0.57) | GAATDP1NPSR1MAPTSMN1; SMN2 | |
| SCHEMBL7499424 | 0.82 | GAA (0.60) | GAATDP1NPSR1MAPTSMN1; SMN2 | |
| SCHEMBL25342487 | 0.81 | GAA (0.51) | GAATDP1NPSR1MAPTSMN1; SMN2 | |
| SCHEMBL8221350 | 0.80 | GAA (0.57) | GAATDP1NPSR1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11123350-B2 | Metal delivery agents and therapeutic uses of the same | THE UNIVERSITY OF MELBOURNE (AU) | 2021-09-21 | — | — | US | disclosed |
| US-20190298734-A1 | Metal Delivery Agents and Therapeutic Uses of the Same | THE UNIVERSITY OF MELBOURNE (AU) | 2019-10-03 | — | — | US | disclosed |
| US-10413554-B2 | Metal delivery agents and therapeutic uses of the same | UNIV MELBOURNE (AU) | 2019-09-17 | — | — | US | disclosed |
| US-20180140613-A1 | Metal Delivery Agents and Therapeutic Uses of the Same | THE UNIVERSITY OF MELBOURNE (AU) | 2018-05-24 | — | — | US | disclosed |
| US-20180140613-A1 | Metal Delivery Agents and Therapeutic Uses of the Same | THE UNIVERSITY OF MELBOURNE (AU) | 2018-05-24 | — | — | US | disclosed |
| EP-3238719-A1 | METAL DELIVERY AGENTS FOR THE TREATMENT OF MULTIPLE SCLEROSIS | The University of Melbourne (AU) | 2017-11-01 | — | — | EP | disclosed |
| EP-2813223-B1 | Metal delivery agents and terapeutic uses of the same | UNIV MELBOURNE (AU) | 2017-10-25 | — | — | EP | disclosed |
| US-20150105461-A1 | Metal Delivery Agents and Therapeutic Uses of the Same | THE UNIVERSITY OF MELBOURNE (AU) | 2015-04-16 | — | — | US | disclosed |
| US-20150105461-A1 | Metal Delivery Agents and Therapeutic Uses of the Same | THE UNIVERSITY OF MELBOURNE (AU) | 2015-04-16 | — | — | US | disclosed |
| EP-2813223-A1 | Metal delivery agents and terapeutic uses of the same | The University of Melbourne (AU) | 2014-12-17 | — | — | EP | disclosed |
| US-20120270850-A1 | METAL DELIVERY AGENTS AND THERAPEUTIC USES OF THE SAME | UNIVERSITY OF MEDLBOURNE (AU) | 2012-10-25 | — | — | US | disclosed |
| US-20120270850-A1 | METAL DELIVERY AGENTS AND THERAPEUTIC USES OF THE SAME | UNIVERSITY OF MEDLBOURNE (AU) | 2012-10-25 | — | — | US | disclosed |
| WO-2008061306-A1 | METAL DELIVERY AGENTS AND THERAPEUTIC USES OF THE SAME | THE UNIVERSITY OF MELBOURNE (AU) | 2008-05-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120270850-A1 | METAL DELIVERY AGENTS AND THERAPEUTIC USES OF THE SAME | SOD1, SLC30A6, SLC30A5 | GAA 93/4885TDP1 1033/4885NPSR1 2215/4885 |
| US-10413554-B2 | Metal delivery agents and therapeutic uses of the same | SOD1, SLC30A6, SLC30A5 | GAA 93/4885TDP1 1029/4885NPSR1 2231/4885 |
| US-20150105461-A1 | Metal Delivery Agents and Therapeutic Uses of the Same | SOD1, SLC30A6, SLC30A5 | GAA 93/4885TDP1 1033/4885NPSR1 2215/4885 |
| US-20180140613-A1 | Metal Delivery Agents and Therapeutic Uses of the Same | SOD1, SLC30A6, SLC30A5 | GAA 93/4885TDP1 1033/4885NPSR1 2215/4885 |
| US-11123350-B2 | Metal delivery agents and therapeutic uses of the same | SOD1, SLC30A6, SLC30A5 | GAA 93/4885TDP1 1033/4885NPSR1 2215/4885 |
| US-20190298734-A1 | Metal Delivery Agents and Therapeutic Uses of the Same | SOD1, SLC30A6, SLC30A5 | GAA 93/4885TDP1 1033/4885NPSR1 2215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.