Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | PNP | P00491 | 1/20 | 0.38 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.38 |
| ▸ | CDK4 | P11802 | 2/20 | 0.38 |
| ▸ | CCND1 | P24385 | 2/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.38 |
| ▸ | PDE9A | O76083 | 1/20 | 0.37 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7503850 | 0.96 | PDE2A (0.42) | PDE2AKMT2AHPGDALDH1A1LMNA | |
| SCHEMBL7512245 | 0.89 | PDE2A (0.41) | PDE2AKMT2AHPGDALDH1A1LMNA | |
| SCHEMBL7500192 | 0.87 | PDE2A (0.55) | PDE2AHPGDALDH1A1CCNE2CDK4 | |
| SCHEMBL7504024 | 0.81 | PDE2A (0.41) | PDE2AKMT2AHPGDALDH1A1LMNA | |
| SCHEMBL1960594 | 0.79 | PDE2A (0.43) | PDE2AKMT2AHPGDATM | |
| SCHEMBL7438629 | 0.77 | PDE2A (0.44) | PDE2AKMT2AHPGDALDH1A1LMNA | |
| SCHEMBL6998879 | 0.75 | PDE2A (0.44) | PDE2AKMT2AALDH1A1CCNE2CDK4 | |
| SCHEMBL2831825 | 0.74 | PDE2A (0.46) | PDE2AKMT2AHPGDPDE9APDE1C | |
| SCHEMBL6992823 | 0.74 | PDE9A (0.53) | PDE2AKMT2APDE9APDE1C | |
| SCHEMBL6051959 | 0.74 | PDE2A (0.63) | PDE2AKMT2ALMNAPNPPDE9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998032755-A1 | PURINE DIONES AS PHOSPHODIESTERASE INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-07-30 | — | — | WO | disclosed |