Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 10/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | EBP | Q15125 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7503850 | 0.89 | PDE2A (0.42) | PDE2ACCNE2CDK4CCND1CCNE1 | |
| SCHEMBL7499444 | 0.87 | PDE2A (0.40) | PDE2ACCNE2CDK4CCND1CCNE1 | |
| SCHEMBL2835216 | 0.81 | PDE2A (0.55) | PDE2APOLBCCNE2CDK4CCND1 | |
| SCHEMBL6991709 | 0.81 | PDE2A (0.58) | PDE2APOLBCCNE2CDK4CCND1 | |
| SCHEMBL4947310 | 0.77 | PDE2A (0.62) | PDE2APOLBCCNE2CDK4CCND1 | |
| SCHEMBL7512245 | 0.76 | PDE2A (0.41) | PDE2ACCNE2CDK4CCND1CCNE1 | |
| SCHEMBL7354927 | 0.76 | PDE2A (0.57) | PDE2APOLBCCNE2CDK4CCND1 | |
| SCHEMBL7000731 | 0.76 | PDE2A (0.57) | PDE2APOLBALDH1A1TP53HPGD | |
| SCHEMBL4163282 | 0.75 | PDE2A (0.62) | PDE2APOLBCCNE2CDK4CCND1 | |
| SCHEMBL6999184 | 0.75 | PDE2A (0.57) | PDE2ACCNE2CDK4CCND1CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998032755-A1 | PURINE DIONES AS PHOSPHODIESTERASE INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-07-30 | — | — | WO | disclosed |