SCHEMBL7499503

SCHEMBL7499503

N#C/N=C1/COCCN1Cc1ccc(Cl)nc1

nearest known ligand 0.58

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 3/20 0.58
MEN1 O00255 1/20 0.58
KMT2A Q03164 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
CHRNB2 P17787 2/20 0.47
CHRNA4 P43681 2/20 0.47
CHRNA1 P02708 2/20 0.44
CHRNA3 P32297 1/20 0.44
ALDH1A1 P00352 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7499506 1.00 CHRNA7 (0.58) CHRNA7MEN1KMT2ATDP1CHRNB2
SCHEMBL675952 0.81 CHRNA7 (0.61) CHRNA7MEN1KMT2ATDP1CHRNB2
SCHEMBL1108456 0.81 CHRNA7 (0.61) CHRNA7MEN1KMT2ATDP1CHRNB2
SCHEMBL9873155 0.78 ALDH1A1 (0.39) CHRNA7MEN1KMT2ATDP1ALDH1A1
SCHEMBL9873157 0.78 ALDH1A1 (0.39) CHRNA7MEN1KMT2ATDP1ALDH1A1
SCHEMBL7735963 0.78 CHRNA7 (0.60) CHRNA7MEN1KMT2ATDP1CHRNB2
SCHEMBL5833213 0.74 CHRNA7 (0.61) CHRNA7MEN1KMT2ATDP1CHRNB2
SCHEMBL5833216 0.74 CHRNA7 (0.61) CHRNA7MEN1KMT2ATDP1CHRNB2
SCHEMBL19975726 0.74 CHRNA7 (0.61) CHRNA7MEN1KMT2ATDP1CHRNB2
Thiacloprid SCHEMBL15757034 0.73 CHRNA7 (1.00) CHRNA7MEN1KMT2ATDP1CHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5034524-A Insecticides NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1991-07-23 US claimed
JP-2235881-A None JP disclosed
JP-6316572-A None JP disclosed
EP-0386565-B2 Heterocyclic compounds BAYER AGROCHEM KK (JP) 2002-07-03 EP disclosed
US-6344453-B1 Insecticidal heterocyclic compounds SHIOKAWA KOZO (JP) 2002-02-05 US disclosed
US-6232309-B1 2-CHLOROPYRIDINE OR 2-CHLOROTHIAZOLE DERIVATIVES OF HETEROCYCLIC COMPOUNDS USED AS PESTICIDES NIHON BAYER AGROCHEM K.K. (JP) 2001-05-15 US disclosed
US-5719146-A AGRICULTURE; FORESTRY; STORAGE; HYGIENE NIHON BAYER AGROCHEM K.K. (JP) 1998-02-17 US disclosed
JP-H06316572-A NEW HETEROCYCLIC COMPOUND AND INSECTICIDE NIPPON BAYERAGROCHEM KK 1994-11-15 JP disclosed
EP-0386565-B1 Heterocyclic compounds BAYER AGROCHEM KK (JP) 1994-01-12 EP disclosed
US-5034524-A Insecticides NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1991-07-23 US disclosed
US-5032589-A Insecticidal heterocyclic compounds NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1991-07-16 US disclosed
JP-H02235881-A NEW HETEROCYCLIC COMPOUND AND INSECTICIDE NIPPON TOKUSHU NOYAKU SEIZO KK 1990-09-18 JP disclosed
EP-0386565-A1 Heterocyclic compounds NIHON BAYER AGROCHEM K.K. (JP) 1990-09-12 EP disclosed