SCHEMBL675952

SCHEMBL675952

N#C/N=C1\CCCN1Cc1ccc(Cl)nc1

nearest known ligand 0.61

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 4/20 0.61
MEN1 O00255 1/20 0.61
KMT2A Q03164 1/20 0.61
TDP1 Q9NUW8 1/20 0.61
CHRNB2 P17787 2/20 0.50
CHRNA4 P43681 2/20 0.50
CHRNA1 P02708 3/20 0.47
CHRNA3 P32297 2/20 0.47
ALDH1A1 P00352 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
TSHR P16473 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1108456 1.00 CHRNA7 (0.61) CHRNA7MEN1KMT2ATDP1CHRNB2
SCHEMBL14389300 0.82 CHRNA7 (0.42) CHRNA7MEN1KMT2ATDP1CHRNB2
SCHEMBL7499503 0.81 CHRNA7 (0.58) CHRNA7MEN1KMT2ATDP1CHRNB2
SCHEMBL7499506 0.81 CHRNA7 (0.58) CHRNA7MEN1KMT2ATDP1CHRNB2
SCHEMBL9070395 0.80 CHRNA1 (0.55) CHRNA7CHRNB2CHRNA4CHRNA1CHRNA3
SCHEMBL9070393 0.80 CHRNA1 (0.55) CHRNA7CHRNB2CHRNA4CHRNA1CHRNA3
SCHEMBL5833743 0.79 CHRNA7 (0.58) CHRNA7MEN1KMT2ATDP1CHRNB2
SCHEMBL7735963 0.79 CHRNA7 (0.60) CHRNA7MEN1KMT2ATDP1CHRNB2
SCHEMBL7961750 0.78 CHRNA7 (0.56) CHRNA7MEN1KMT2ATDP1CHRNB2
SCHEMBL9014867 0.78 CHRNA1 (0.55) CHRNA7CHRNB2CHRNA4CHRNA1CHRNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9919979-B2 Fertilizer-compatible composition BAYER CROPSCIENCE LP (US) 2018-03-20 US disclosed
US-9919979-B2 Fertilizer-compatible composition BAYER CROPSCIENCE LP (US) 2018-03-20 US disclosed
US-9662309-B2 Anti-demodicosis agent BAYER INTELLECTUAL PROPERTY GMBH (DE) 2017-05-30 US disclosed
US-9662309-B2 Anti-demodicosis agent BAYER INTELLECTUAL PROPERTY GMBH (DE) 2017-05-30 US disclosed
US-8993483-B2 Combination of active substances with insecticidal properties BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-03-31 US disclosed
US-8993483-B2 Combination of active substances with insecticidal properties BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-03-31 US disclosed
US-8841294-B2 Active ingredient combinations having insecticidal and acaricidal properties BAYER CROPSCIENCE AG (DE) 2014-09-23 US disclosed
US-8841294-B2 Active ingredient combinations having insecticidal and acaricidal properties BAYER CROPSCIENCE AG (DE) 2014-09-23 US disclosed
US-8728507-B2 Non-systemic control of parasites BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-05-20 US disclosed
US-8728507-B2 Non-systemic control of parasites BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-05-20 US disclosed
US-7312204-B2 Insecticides BAYER AKTIENGESELLSCHAFT (DE) 2007-12-25 US disclosed
US-7312204-B2 Insecticides BAYER AKTIENGESELLSCHAFT (DE) 2007-12-25 US disclosed
US-20070275971-A1 Insecticidal compositions ERDELEN CHRISTOPH 2007-11-29 US disclosed
US-20070232598-A1 Combination of Active Substances with Insecticidal Properties BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2007-10-04 US disclosed
US-20070232598-A1 Combination of Active Substances with Insecticidal Properties BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2007-10-04 US disclosed
US-20070157507-A1 Method of controlling termites BAYER CROPSCIENCE LP 2007-07-12 US disclosed
US-20070157507-A1 Method of controlling termites BAYER CROPSCIENCE LP 2007-07-12 US disclosed
US-7214701-B2 Active substance combinations having insecticidal and acaricdal properties BAYER CROPSCIENCE AG (DE) 2007-05-08 US disclosed
US-7214701-B2 Active substance combinations having insecticidal and acaricdal properties BAYER CROPSCIENCE AG (DE) 2007-05-08 US disclosed
WO-2007025669-A2 ACTIVE SUBSTANCE COMBINATIONS WITH INSECTICIDAL AND ACARICIDAL PROPERTIES BAYER CROPSCIENCE AG (DE) 2007-03-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070275971-A1 Insecticidal compositions CBR3, CBR1, CNPY3 CHRNA7 127/4885MEN1 2348/4885KMT2A 2488/4885
US-20070232598-A1 Combination of Active Substances with Insecticidal Properties ACHE, CHRM3, CHRNA2 CHRNA7 10/4885MEN1 3876/4885KMT2A 698/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.