Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8801602 | 0.91 | CYP1A2 (0.40) | SMN1; SMN2EGLN1GAAKDM4ECYP1A2 | |
| SCHEMBL27442896 | 0.81 | TSHR (0.48) | EGLN1GAAKDM4EALDH1A1HPGD | |
| SCHEMBL7505537 | 0.80 | KDM4E (0.48) | SMN1; SMN2EGLN1GAAKDM4ELMNA | |
| SCHEMBL7500533 | 0.80 | SMN1; SMN2 (0.41) | SMN1; SMN2GAAKDM4ECYP1A2LMNA | |
| SCHEMBL27638748 | 0.79 | SMN1; SMN2 (0.40) | SMN1; SMN2EGLN1GAAKDM4ELMNA | |
| SCHEMBL10878348 | 0.79 | SMN1; SMN2 (0.40) | SMN1; SMN2GAAKDM4ECYP1A2LMNA | |
| Acetic Acid SCHEMBL8807985 | 0.77 | KDM4E (0.46) | SMN1; SMN2EGLN1GAAKDM4ELMNA | |
| SCHEMBL7505743 | 0.77 | KDM4E (0.41) | SMN1; SMN2GAAKDM4ECYP1A2LMNA | |
| SCHEMBL24800386 | 0.77 | NPSR1 (0.42) | SMN1; SMN2EGLN1GAAKDM4ECYP1A2 | |
| SCHEMBL14966319 | 0.74 | LMNA (0.36) | EGLN1LMNADPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634405-B1 | Pyrimidinyl acrylic acid derivatives, process for their preparation and their use for the control of phytopathogens | BAYER AG (DE) | 2002-10-30 | — | — | EP | disclosed |
| US-5635508-A | FUNGICIDES | NOVARTIS AG (CH) | 1997-06-03 | — | — | US | disclosed |
| US-5453427-A | Control phytopathogenic fungi especially in monocotelydons, podery mildew and rust | SANDOZ LTD. (CH) | 1995-09-26 | — | — | US | disclosed |
| EP-0634405-A1 | Pyrimidinyl acrylic acid derivatives, process for their preparation and their use for the control of phytopathogens | SANDOZ LTD. (CH) | 1995-01-18 | — | — | EP | disclosed |