Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.73 |
| ▸ | QDPR | P09417 | 4/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | KMO | O15229 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11108930 | 0.87 | ACMSD (0.59) | ACMSDQDPRHDAC8HDAC4HDAC2 | |
| SCHEMBL27965931 | 0.85 | ACMSD (1.00) | ACMSDHDAC8HDAC4HDAC2KMO | |
| SCHEMBL2533359 | 0.85 | ACMSD (1.00) | ACMSDHDAC8HDAC4HDAC2KMO | |
| SCHEMBL7147506 | 0.84 | ACMSD (0.54) | ACMSDQDPRHDAC8HDAC4HDAC2 | |
| SCHEMBL11325708 | 0.82 | ACMSD (0.71) | ACMSDHDAC8HDAC4HDAC2KMO | |
| SCHEMBL11312879 | 0.82 | ACMSD (0.71) | ACMSDHDAC8HDAC4HDAC2KMO | |
| SCHEMBL1415417 | 0.80 | ACMSD (0.51) | ACMSDQDPRKMT2A | |
| SCHEMBL10886997 | 0.80 | ACMSD (0.68) | ACMSDQDPRHDAC8HDAC4HDAC2 | |
| SCHEMBL24605452 | 0.79 | ACMSD (0.69) | ACMSDQDPRHDAC8HDAC4HDAC2 | |
| SCHEMBL8470022 | 0.79 | ACMSD (0.50) | ACMSDHDAC8KMOCYP2D6DEGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0924202-B1 | Imidazole derivative and medicine comprising the same as active ingredient | SSP CO LTD (JP) | 2002-05-29 | — | — | EP | disclosed |
| US-6071943-A | IMMUNOMODULATORS WHICH SUPPRESS SPECIFIC CYTOKINES, FOR AUTOIMMUNE DISEASES | SSP CO. LTD. (JP) | 2000-06-06 | — | — | US | disclosed |
| EP-0924202-A1 | Imidazole derivative and medicine comprising the same as active ingredient | SSP Co., Ltd. (JP) | 1999-06-23 | — | — | EP | disclosed |
| US-RE32196-E | PROPHYLACTIC CHEMOTHERAPY OF ALLERGIC CONDITIONS | LILLY INDUSTRIES LIMITED (GB) | 1986-07-01 | — | — | US | disclosed |
| US-4281012-A | HYPOLIPEMIC ACTIVITY | ROUSSEL UCLAF (FR) | 1981-07-28 | — | — | US | disclosed |
| US-4259340-A | PROPHYLACTIC CHEMOTHERAPY OF ALLERGIC CONDITIONS SUCH AS ASTHMA | LILLY INDUSTRIES LIMITED (GB) | 1981-03-31 | — | — | US | disclosed |