Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.71 |
| ▸ | DEGS1 | O15121 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.44 |
| ▸ | KMO | O15229 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11312879 | 1.00 | ACMSD (0.71) | ACMSDDEGS1HDAC8HDAC6HDAC1 | |
| SCHEMBL24605452 | 0.87 | ACMSD (0.69) | ACMSDDEGS1HDAC8HDAC6HDAC1 | |
| SCHEMBL2533359 | 0.83 | ACMSD (1.00) | ACMSDHDAC8KDM4EHTTSMN1; SMN2 | |
| SCHEMBL27965931 | 0.83 | ACMSD (1.00) | ACMSDHDAC8KDM4EHTTSMN1; SMN2 | |
| SCHEMBL7499690 | 0.82 | ACMSD (0.73) | ACMSDDEGS1HDAC8HDAC6HDAC1 | |
| SCHEMBL10886997 | 0.78 | ACMSD (0.68) | ACMSDDEGS1HDAC8HDAC6HDAC1 | |
| SCHEMBL19013936 | 0.76 | HDAC8 (0.57) | ACMSDDEGS1HDAC8HDAC6HDAC1 | |
| SCHEMBL1856511 | 0.75 | ACMSD (0.53) | ACMSDKDM4ELMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL68815 | 0.75 | QDPR (0.66) | ACMSDHDAC8HDAC4HDAC2SERPINE1 | |
| SCHEMBL9450662 | 0.75 | ACMSD (0.76) | ACMSDHDAC8KDM4ELMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4306930-A | INCORPORATING A HYDRAZIDE OR DIHYDRAZIDE AND THEN VULCANIZING IN CONTACT WITH A METAL | CIBA-GEIGY CORPORATION (US) | 1981-12-22 | — | — | US | disclosed |
| US-4077948-A | N-SALICYLIDENE-N*-SALICYLHYDRAZIDES | CIBA-GEIGY CORPORATION (US) | 1978-03-07 | — | — | US | disclosed |
| US-3994987-A | Metal deactivators as adhesion promotors for vulcanizable elastomers to metals | CIBA-GEIGY CORPORATION (US) | 1976-11-30 | — | — | US | disclosed |