Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7498327 | 0.85 | OPRM1 (0.35) | OPRM1OPRL1MMP2MMP3MMP9 | |
| SCHEMBL7497849 | 0.84 | KDM1A (0.38) | OPRM1OPRL1MMP2MMP3MMP9 | |
| SCHEMBL7488373 | 0.82 | OPRM1 (0.34) | OPRM1OPRL1MMP2MMP3MMP9 | |
| SCHEMBL8991007 | 0.81 | — | — | |
| SCHEMBL7495764 | 0.77 | NPSR1 (0.37) | CYP1A2CYP2C9CYP2C19NPSR1KDM4E | |
| SCHEMBL8991380 | 0.72 | KDM1A (0.35) | — | |
| SCHEMBL7488740 | 0.69 | OPRM1 (0.40) | OPRM1OPRL1MMP2MMP3MMP9 | |
| SCHEMBL8991282 | 0.68 | — | — | |
| SCHEMBL14778726 | 0.66 | OPRM1 (0.45) | OPRM1OPRL1MMP2MMP3MMP9 | |
| SCHEMBL14777608 | 0.64 | OPRM1 (0.43) | OPRM1OPRL1MMP2MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646183-A | Phenyl amidine alkanoic acids useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1997-07-08 | — | — | US | disclosed |
| US-5612355-A | Phenyl amidine lactones useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1997-03-18 | — | — | US | disclosed |