Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 11/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991475 | 0.80 | CYP19A1 (0.39) | CYP19A1 | |
| SCHEMBL16915056 | 0.75 | MEN1 (0.40) | CYP19A1 | |
| SCHEMBL8923932 | 0.71 | GRIN2D (0.48) | CYP19A1MMP2MMP3MMP9 | |
| SCHEMBL576582 | 0.70 | ALDH1A1 (0.39) | MMP2MMP9 | |
| SCHEMBL576431 | 0.70 | MEN1 (0.38) | — | |
| SCHEMBL7499785 | 0.69 | OPRM1 (0.36) | OPRM1OPRL1MMP2MMP3MMP9 | |
| SCHEMBL3340035 | 0.69 | SIRT2 (0.32) | — | |
| SCHEMBL3678845 | 0.69 | KCNA3 (0.36) | — | |
| SCHEMBL7498327 | 0.69 | OPRM1 (0.35) | OPRM1OPRL1MMP2MMP3MMP9 | |
| SCHEMBL15043648 | 0.68 | GRIN2D (0.47) | OPRM1OPRL1CYP19A1MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646183-A | Phenyl amidine alkanoic acids useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1997-07-08 | — | — | US | disclosed |
| US-5612355-A | Phenyl amidine lactones useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1997-03-18 | — | — | US | disclosed |
| US-5504106-A | Phenyl amidine alkanoic acids and lactones useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1996-04-02 | — | — | US | disclosed |