Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SENP1 | Q9P0U3 | 6/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.45 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.43 |
| ▸ | MEF2D | Q14814 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ROS1 | P08922 | 1/20 | 0.42 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7499852 | 1.00 | SENP1 (0.46) | SENP1ROCK1SENP2HDAC4MEF2D | |
| SCHEMBL8304013 | 0.91 | KDM4E (0.43) | MAPK1TDP1PTGS2KDM4ENPC1 | |
| SCHEMBL7497378 | 0.87 | SENP1 (0.53) | SENP1ROCK1SENP2HDAC4MEF2D | |
| SCHEMBL7497385 | 0.87 | SENP1 (0.53) | SENP1ROCK1SENP2HDAC4MEF2D | |
| SCHEMBL7500209 | 0.84 | ITGB3 (0.58) | HDAC4HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL7500205 | 0.84 | ITGB3 (0.58) | HDAC4HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL7500334 | 0.83 | ITGB3 (0.59) | — | |
| SCHEMBL7500332 | 0.83 | ITGB3 (0.59) | — | |
| SCHEMBL7494300 | 0.82 | SENP1 (0.55) | SENP1SENP2MAPK1PTGS2NAMPT | |
| SCHEMBL7494303 | 0.82 | SENP1 (0.55) | SENP1SENP2MAPK1PTGS2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894084-B1 | CINNAMIC ACID DERIVATIVES AND THEIR USE AS INTEGRIN ANTAGONISTS | SEARLE & CO (US) | 2002-06-26 | — | — | EP | claimed |
| EP-0894084-A1 | CINNAMIC ACID DERIVATIVES AND THEIR USE AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1999-02-03 | — | — | EP | claimed |
| WO-1997036860-A1 | CINNAMIC ACID DERIVATIVES AND THEIR USE AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1997-10-09 | — | — | WO | claimed |
| EP-0894084-B1 | CINNAMIC ACID DERIVATIVES AND THEIR USE AS INTEGRIN ANTAGONISTS | SEARLE & CO (US) | 2002-06-26 | — | — | EP | disclosed |