Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7503826 | 0.88 | KCNH2 (0.37) | KCNH2SCN5AKDM4EALDH1A1LMNA | |
| SCHEMBL7504904 | 0.87 | ALDH1A1 (0.40) | TOP1KCNH2SCN5APIM1PIM3 | |
| SCHEMBL7502899 | 0.87 | ALDH1A1 (0.40) | TOP1KCNH2SCN5APIM1PIM3 | |
| SCHEMBL7546411 | 0.87 | ALDH1A1 (0.40) | TOP1KCNH2SCN5APIM1PIM3 | |
| SCHEMBL8569098 | 0.86 | KCNH2 (0.42) | TOP1KCNH2SCN5APIM1PIM3 | |
| SCHEMBL8569090 | 0.86 | KCNH2 (0.42) | TOP1KCNH2SCN5APIM1PIM3 | |
| SCHEMBL7503507 | 0.86 | KDM4E (0.35) | KCNH2SCN5AKDM4EALDH1A1HPGD | |
| SCHEMBL7497603 | 0.86 | KCNH2 (0.35) | KCNH2SCN5A | |
| SCHEMBL7506175 | 0.86 | KCNH2 (0.35) | KCNH2SCN5A | |
| Hydrochloric Acid SCHEMBL7502024 | 0.85 | KCNH2 (0.42) | TOP1KCNH2SCN5APIM1PIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723545-B1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LAB (US) | 2002-05-08 | — | — | EP | claimed |