SCHEMBL7500154

SCHEMBL7500154

COC=C(C(=O)OC)c1ccccc1CON=C(C)C(=NOC)c1ccc(CCc2cccc(C(F)(F)F)c2)cc1

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 7/20 0.47
MAOB P27338 1/20 0.36
KDM4E B2RXH2 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
HDAC1 Q13547 1/20 0.34
HDAC8 Q9BY41 1/20 0.34
MAPK14 Q16539 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7498432 0.94 HIF1A (0.50) HIF1A
SCHEMBL7871723 0.91 HIF1A (0.47) HIF1AMAOB
SCHEMBL6839881 0.91 HIF1A (0.53) HIF1AMAOB
SCHEMBL7742946 0.87 HIF1A (0.48) HIF1AMAOB
SCHEMBL7742949 0.87 HIF1A (0.48) HIF1AMAOB
SCHEMBL7465781 0.85 MAOB (0.47) HIF1AMAOB
SCHEMBL7462687 0.85 MAOB (0.47) HIF1AMAOB
SCHEMBL7465783 0.85 MAOB (0.47) HIF1AMAOB
SCHEMBL7868778 0.83 HIF1A (0.43) HIF1AMAOB
SCHEMBL7497703 0.83 MAOB (0.45) HIF1AMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6420423-B1 PESTICIDE FOR USE ON CEREALS, BEETS, FRUITS, BERRIES, AND BEANS; KILLS MITES, INSECTS, TERMITES, LICE, FLEAS, AND FUNGUS; TOLERATED WELL BE ANIMALS, PLANTS, AND FISH BAYER AKTIENGESELLSCHAFT (DE) 2002-07-16 US disclosed
EP-1207152-A2 Pesticides Bayer Aktiengesellschaft (DE) 2002-05-22 EP disclosed
US-5985921-A OXIDATION AND HYDROGENATION OF COMPOUNDS TO FORM INSECTICIDES AS AGROCHEMICALS NOVARTIS CORPORATION (US) 1999-11-16 US disclosed
EP-0865424-A1 PESTICIDES Novartis AG (CH) 1998-09-23 EP disclosed
WO-1997020809-A1 PESTICIDES NOVARTIS AG (CH) 1997-06-12 WO disclosed