SCHEMBL7868778

SCHEMBL7868778

CO/C=C(/C(=O)OC)c1ccccc1CO/N=C(C)/C(=N\OC)c1ccc(OCC#Cc2cccc(C(F)(F)F)c2)cc1

nearest known ligand 0.43

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.43
MAOB P27338 1/20 0.35
EGLN1 Q9GZT9 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6839881 0.88 HIF1A (0.53) HIF1AMAOB
SCHEMBL7871723 0.85 HIF1A (0.47) HIF1AMAOB
SCHEMBL7500154 0.83 HIF1A (0.47) HIF1AMAOB
SCHEMBL6841529 0.83 MAOB (0.45) HIF1AMAOB
SCHEMBL7736847 0.83 MAOB (0.45) HIF1AMAOB
SCHEMBL7462687 0.82 MAOB (0.47) HIF1AMAOB
SCHEMBL7465781 0.82 MAOB (0.47) HIF1AMAOB
SCHEMBL7465783 0.82 MAOB (0.47) HIF1AMAOB
SCHEMBL7467255 0.81 HIF1A (0.41) HIF1ARXFP1
SCHEMBL7467258 0.81 HIF1A (0.41) HIF1ARXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6313344-B1 PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2001-11-06 US disclosed