SCHEMBL7871723

SCHEMBL7871723

CO/C=C(/C(=O)OC)c1ccccc1CO/N=C(C)/C(=N\OC)c1ccc(OCCCc2cccc(C(F)(F)F)c2)cc1

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 7/20 0.47
MAOB P27338 2/20 0.40
NR4A2 P43354 1/20 0.37
SLC2A1 P11166 1/20 0.37
SIRT2 Q8IXJ6 1/20 0.36
MAPT P10636 1/20 0.35
HTT P42858 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
SPHK2 Q9NRA0 1/20 0.35
SPHK1 Q9NYA1 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6839881 0.93 HIF1A (0.53) HIF1AMAOBNR4A2MAPTHTT
SCHEMBL7500154 0.91 HIF1A (0.47) HIF1AMAOB
SCHEMBL7493117 0.88 MAOB (0.45) HIF1AMAOBNR4A2MAPTHTT
SCHEMBL7493118 0.88 MAOB (0.45) HIF1AMAOBNR4A2MAPTHTT
SCHEMBL7465783 0.87 MAOB (0.47) HIF1AMAOBNR4A2MAPTHTT
SCHEMBL7465781 0.87 MAOB (0.47) HIF1AMAOBNR4A2MAPTHTT
SCHEMBL7462687 0.87 MAOB (0.47) HIF1AMAOBNR4A2MAPTHTT
SCHEMBL7497699 0.85 MAOB (0.45) HIF1AMAOBNR4A2MAPTHTT
SCHEMBL7868778 0.85 HIF1A (0.43) HIF1AMAOB
SCHEMBL7497703 0.85 MAOB (0.45) HIF1AMAOBNR4A2MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6313344-B1 PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2001-11-06 US disclosed