Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | EDNRB | P24530 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2072032 | 0.93 | LMNA (0.40) | CYP3A4MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL2071208 | 0.93 | LMNA (0.40) | CYP3A4MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL2069840 | 0.93 | LMNA (0.40) | CYP3A4MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL7553469 | 0.93 | LMNA (0.40) | CYP3A4MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL2072034 | 0.93 | LMNA (0.40) | CYP3A4MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL2069577 | 0.92 | CYP3A4 (0.38) | CYP3A4MAPTL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL2069182 | 0.92 | CYP3A4 (0.38) | CYP3A4MAPTL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL2071317 | 0.88 | LMNA (0.37) | CYP3A4MAPTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL2069335 | 0.88 | LMNA (0.37) | CYP3A4MAPTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL2072015 | 0.88 | LMNA (0.37) | CYP3A4MAPTALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1153020-A4 | PRODUCTION OF ISOFLAVONE DERIVATIVES | NOVOGEN RES PTY LTD (AU) | 2002-08-21 | — | — | EP | disclosed |
| EP-1153020-A1 | PRODUCTION OF ISOFLAVONE DERIVATIVES | Novogen Research Pty. Ltd. (AU) | 2001-11-14 | — | — | EP | disclosed |
| WO-2000049009-A1 | PRODUCTION OF ISOFLAVONE DERIVATIVES | NOVOGEN RESEARCH PTY. LTD. (AU) | 2000-08-24 | — | — | WO | disclosed |