Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2072032 | 1.00 | LMNA (0.40) | LMNACYP3A4PTPN1ACHEKMT2A | |
| SCHEMBL2072034 | 1.00 | LMNA (0.40) | LMNACYP3A4PTPN1ACHEKMT2A | |
| SCHEMBL2069840 | 1.00 | LMNA (0.40) | LMNACYP3A4PTPN1ACHEKMT2A | |
| SCHEMBL2071208 | 1.00 | LMNA (0.40) | LMNACYP3A4PTPN1ACHEKMT2A | |
| SCHEMBL7500189 | 0.93 | CYP3A4 (0.39) | LMNACYP3A4PTPN1KMT2ASMN1; SMN2 | |
| SCHEMBL4427157 | 0.89 | ACHE (0.37) | LMNACYP3A4PTPN1ACHEGBA1 | |
| SCHEMBL4427159 | 0.89 | ACHE (0.37) | LMNACYP3A4PTPN1ACHEGBA1 | |
| SCHEMBL2072017 | 0.88 | LMNA (0.37) | LMNACYP3A4PTPN1ACHEKMT2A | |
| SCHEMBL2071317 | 0.88 | LMNA (0.37) | LMNACYP3A4PTPN1ACHEKMT2A | |
| SCHEMBL2069335 | 0.88 | LMNA (0.37) | LMNACYP3A4PTPN1ACHEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1153020-A4 | PRODUCTION OF ISOFLAVONE DERIVATIVES | NOVOGEN RES PTY LTD (AU) | 2002-08-21 | — | — | EP | disclosed |
| EP-1153020-A1 | PRODUCTION OF ISOFLAVONE DERIVATIVES | Novogen Research Pty. Ltd. (AU) | 2001-11-14 | — | — | EP | disclosed |
| WO-2000049009-A1 | PRODUCTION OF ISOFLAVONE DERIVATIVES | NOVOGEN RESEARCH PTY. LTD. (AU) | 2000-08-24 | — | — | WO | disclosed |