Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLOD2 | O00469 | 3/20 | 0.40 |
| ▸ | PLOD3 | O60568 | 2/20 | 0.39 |
| ▸ | PLOD1 | Q02809 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 8/20 | 0.37 |
| ▸ | CES1 | P23141 | 7/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL183178 | 0.81 | PLOD2 (0.46) | PLOD2PLOD3PLOD1FAAHCES1 | |
| SCHEMBL3679166 | 0.80 | — | — | |
| SCHEMBL6517983 | 0.78 | PLOD2 (0.44) | PLOD2PLOD3PLOD1FAAHCES1 | |
| SCHEMBL9283764 | 0.78 | PLOD2 (0.44) | PLOD2PLOD3PLOD1FAAHCES1 | |
| SCHEMBL9326020 | 0.78 | PLOD2 (0.44) | PLOD2PLOD3PLOD1FAAHCES1 | |
| Water SCHEMBL7197275 | 0.78 | PLOD2 (0.44) | PLOD2PLOD3PLOD1FAAHCES1 | |
| SCHEMBL6520648 | 0.78 | PLOD2 (0.44) | PLOD2PLOD3PLOD1FAAHCES1 | |
| Water SCHEMBL7191917 | 0.78 | PLOD2 (0.44) | PLOD2PLOD3PLOD1FAAHCES1 | |
| SCHEMBL7213763 | 0.78 | PLOD2 (0.44) | PLOD2PLOD3PLOD1FAAHCES1 | |
| SCHEMBL31182132 | 0.78 | PLOD2 (0.44) | PLOD2PLOD3PLOD1FAAHCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948482-B1 | METHOD FOR PRODUCING TRIFLUOROACETOACETIC ACID ANILIDES | BAYER AG (DE) | 2002-04-03 | — | — | EP | claimed |
| US-6136975-A | Method for producing trifluoroacetoacetic acid anilides | BAYER AKTIENGESELLSCHAFT (DE) | 2000-10-24 | — | — | US | claimed |
| WO-2023237027-A1 | COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF IN PREPARING BICYCLOPYRONE INTERMEDIATE | 山东潍坊润丰化工股份有限公司 | 2023-12-14 | — | — | WO | disclosed |
| CN-115232008-A | Compound, preparation method thereof and application of compound in preparation of fluroxypyr intermediate | 山东潍坊润丰化工股份有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-114716320-B | Compound, preparation method thereof and application of compound in preparation of fluroxypyr intermediate | 山东潍坊润丰化工股份有限公司 | 2022-09-27 | — | — | CN | disclosed |
| CN-114716320-A | Compound, preparation method thereof and application of compound in preparation of fluroxypyr intermediate | 山东潍坊润丰化工股份有限公司 | 2022-07-08 | — | — | CN | disclosed |
| WO-2015004035-A1 | METHOD FOR PREPARATION OF 4-ALKOXY-1,1,1-TRIFLUOROBUT-3-EN-2-ONES FROM TRIFLUOROACETYLACETIC ACID | LONZA LTD (CH) | 2015-01-15 | — | — | WO | disclosed |
| WO-2015004035-A1 | METHOD FOR PREPARATION OF 4-ALKOXY-1,1,1-TRIFLUOROBUT-3-EN-2-ONES FROM TRIFLUOROACETYLACETIC ACID | LONZA LTD (CH) | 2015-01-15 | — | — | WO | disclosed |
| EP-2821399-A1 | Method for preparation of 6-trifluoromethylpyridine-3-carboxylic acid derivatives from 4,4,4-trifluoro-3-oxobutanoyl chloride | Lonza Ltd (CH) | 2015-01-07 | — | — | EP | disclosed |
| EP-2821399-A1 | Method for preparation of 6-trifluoromethylpyridine-3-carboxylic acid derivatives from 4,4,4-trifluoro-3-oxobutanoyl chloride | Lonza Ltd (CH) | 2015-01-07 | — | — | EP | disclosed |
| EP-2821399-A1 | Method for preparation of 6-trifluoromethylpyridine-3-carboxylic acid derivatives from 4,4,4-trifluoro-3-oxobutanoyl chloride | Lonza Ltd (CH) | 2015-01-07 | — | — | EP | disclosed |
| EP-2818461-A1 | Method for preparation of 6-trifluoromethylpyridine-3-carboxylic acid derivatives from 4,4,4-trifluoro-3-oxobutanoyl chloride | Lonza Ltd (CH) | 2014-12-31 | — | — | EP | disclosed |
| EP-2818461-A1 | Method for preparation of 6-trifluoromethylpyridine-3-carboxylic acid derivatives from 4,4,4-trifluoro-3-oxobutanoyl chloride | Lonza Ltd (CH) | 2014-12-31 | — | — | EP | disclosed |
| EP-2818461-A1 | Method for preparation of 6-trifluoromethylpyridine-3-carboxylic acid derivatives from 4,4,4-trifluoro-3-oxobutanoyl chloride | Lonza Ltd (CH) | 2014-12-31 | — | — | EP | disclosed |
| CN-1100754-C | Preparation method of trifluoroacetylacetanilide | BAYER AG (DE) | 2003-02-05 | — | — | CN | disclosed |
| US-6136975-A | Method for producing trifluoroacetoacetic acid anilides | BAYER AKTIENGESELLSCHAFT (DE) | 2000-10-24 | — | — | US | disclosed |
| US-6136975-A | Method for producing trifluoroacetoacetic acid anilides | BAYER AKTIENGESELLSCHAFT (DE) | 2000-10-24 | — | — | US | disclosed |
| CN-1240423-A | Preparation method of trifluoroacetylacetanilide | BAYER AG (DE) | 2000-01-05 | — | — | CN | disclosed |
| WO-1995032952-A1 | PROCESS FOR THE PREPARATION OF 3-ARYLURACILS | CIBA-GEIGY AG (CH) | 1995-12-07 | — | — | WO | disclosed |
| US-4785129-A | Methyl 4,4,4-trifluoro-3-oxo-butanethioate | MONSANTO COMPANY (US) | 1988-11-15 | — | — | US | disclosed |