Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PAM | P19021 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27759597 | 0.85 | L3MBTL1 (0.50) | TSHRALDH1A1L3MBTL1MAPK1KDM4E | |
| SCHEMBL27516923 | 0.84 | TSHR (0.53) | TSHRALDH1A1L3MBTL1MAPK1CES2 | |
| SCHEMBL1948655 | 0.83 | CA12 (0.50) | TSHRALDH1A1L3MBTL1MAPK1PAM | |
| SCHEMBL27592314 | 0.83 | ALDH1A1 (0.66) | ALDH1A1L3MBTL1MAPK1LMNAPAM | |
| SCHEMBL9006857 | 0.83 | TDP1 (0.56) | ALDH1A1L3MBTL1KDM4ELMNATDP1 | |
| SCHEMBL28478049 | 0.81 | TSHR (0.50) | TSHRALDH1A1L3MBTL1MAPK1CES2 | |
| Benzene SCHEMBL28096336 | 0.81 | ALDH1A1 (0.62) | TSHRALDH1A1L3MBTL1MAPK1CES2 | |
| SCHEMBL4675 | 0.81 | ALDH1A1 (0.62) | TSHRALDH1A1L3MBTL1MAPK1CES2 | |
| SCHEMBL1870609 | 0.81 | ALDH1A1 (0.62) | TSHRALDH1A1L3MBTL1MAPK1CES2 | |
| SCHEMBL16936971 | 0.80 | L3MBTL1 (0.52) | TSHRALDH1A1L3MBTL1MAPK1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2430014-A1 | ANTIVIRAL COMPOUNDS | Gilead Sciences, Inc. (US) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010132601-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2010-11-18 | — | — | WO | disclosed |