SCHEMBL7500293

SCHEMBL7500293

O=CNCc1csc2cncn12

nearest known ligand 0.30

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ADH1B P00325 1/20 0.30
ADH1C P00326 1/20 0.30
ADH1A P07327 1/20 0.30
ADH7 P40394 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7496497 0.77 TBXAS1 (0.30)
SCHEMBL8059100 0.73 IDO1 (0.36)
SCHEMBL7498371 0.70
SCHEMBL7498841 0.70 IDO1 (0.38)
SCHEMBL7492772 0.70 IDO1 (0.36)
SCHEMBL16708772 0.68 CHRM5 (0.39) ADH1BADH1CADH1AADH7
SCHEMBL7491722 0.66 ADH1B (0.30) ADH1BADH1CADH1AADH7
SCHEMBL7491719 0.62 ADH1B (0.30) ADH1BADH1CADH1AADH7
SCHEMBL8052735 0.61 KDM4E (0.32)
SCHEMBL7491989 0.60 CCNC (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0760370-B1 NOVEL CARBAPENEM DERIVATIVES MEIJI SEIKA CO (JP) 2002-08-07 EP disclosed
EP-0669336-B1 NOVEL CEPHEM DERIVATIVES MEIJI SEIKA CO (JP) 2000-05-17 EP disclosed
US-5990101-A Carbapenem derivatives MEIJI SEIKA KABUSHIKI KAISHA (JP) 1999-11-23 US disclosed
US-5663162-A BACTERICIDES AND ANTIBIOTICS MEIJI SEIKA KABUSHIKI KAISHA (JP) 1997-09-02 US disclosed
EP-0760370-A1 NOVEL CARBAPENEM DERIVATIVES MEIJI SEIKA KABUSHIKI KAISHA (JP) 1997-03-05 EP disclosed
EP-0669336-A1 NOVEL CEPHEM DERIVATIVE MEIJI SEIKA KABUSHIKI KAISHA (JP) 1995-08-30 EP disclosed