SCHEMBL2298254

SCHEMBL2298254

O=C(Nc1cccc(NC(=O)c2ccccc2)c1)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KCNK3 O14649 11/20 1.00
KCNK9 Q9NPC2 9/20 1.00
SIRT1 Q96EB6 1/20 0.85
KMT2A Q03164 5/20 0.79
MEN1 O00255 4/20 0.79
TP53 P04637 1/20 0.79
POLB P06746 1/20 0.77
NPC1 O15118 2/20 0.76
RAB9A P51151 2/20 0.76
HPGD P15428 1/20 0.76
ALDH1A1 P00352 1/20 0.72
MAPT P10636 1/20 0.72
LPAR3 Q9UBY5 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14715912 0.96 KCNK3 (0.92) KCNK3KCNK9SIRT1KMT2AMEN1
SCHEMBL14715827 0.96 KCNK3 (0.92) KCNK3KCNK9SIRT1KMT2AMEN1
SCHEMBL18953533 0.94 KCNK3 (0.89) KCNK3KCNK9SIRT1KMT2AMEN1
SCHEMBL14715832 0.94 KCNK3 (0.88) KCNK3KCNK9SIRT1KMT2AMEN1
SCHEMBL19491390 0.92 SIRT1 (1.00) KCNK3KCNK9SIRT1KMT2AMEN1
SCHEMBL14715821 0.92 KCNK3 (0.85) KCNK3KCNK9SIRT1KMT2AMEN1
SCHEMBL22305399 0.91 KCNK3 (0.83) KCNK3KCNK9SIRT1KMT2AMEN1
SCHEMBL23577148 0.91 KCNK3 (0.82) KCNK3KCNK9SIRT1KMT2AMEN1
SCHEMBL7745878 0.91 KCNK3 (0.82) KCNK3KCNK9SIRT1KMT2AMEN1
SCHEMBL7739117 0.91 KCNK3 (0.82) KCNK3KCNK9SIRT1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021241913-A1 PHENYLENE DIBENZAMIDE COMPOUND, AND PHARMACEUTICAL COMPOSITION, FOR PREVENTING OR TREATING CANCER DISEASES, COMPRISING SAME AS ACTIVE INGREDIENT 주식회사 헤지호그 2021-12-02 WO disclosed
US-20160074817-A1 Halogen Resistant Amides, Polyamides, and Membranes Made From the Same THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE INTERIOR (US) 2016-03-17 US disclosed
US-20160074817-A1 Halogen Resistant Amides, Polyamides, and Membranes Made From the Same THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE INTERIOR (US) 2016-03-17 US disclosed
US-20140263024-A1 HALOGEN RESISTANT AMIDES, POLYAMIDES, AND MEMBRANES MADE FROM THE SAME MURPHY ANDREW PATRICK (US) 2014-09-18 US disclosed
US-20140263024-A1 HALOGEN RESISTANT AMIDES, POLYAMIDES, AND MEMBRANES MADE FROM THE SAME MURPHY ANDREW PATRICK (US) 2014-09-18 US disclosed
US-20140263024-A1 HALOGEN RESISTANT AMIDES, POLYAMIDES, AND MEMBRANES MADE FROM THE SAME MURPHY ANDREW PATRICK (US) 2014-09-18 US disclosed
EP-2318389-B1 PYRIDAZINE DERIVATIVES AS SMO INHIBITORS NOVARTIS AG (CH) 2013-06-19 EP disclosed
US-8466180-B2 Insecticidal compounds SYNGENTA CROP PROTECTION LLC (US) 2013-06-18 US disclosed
US-8377530-B2 Polyesters with low molecular weight additives for improved gas barrier properties EASTMAN CHEMICAL COMPANY (US) 2013-02-19 US disclosed
US-20120199515-A1 POLYESTERS WITH LOW MOLECULAR WEIGHT ADDITIVES FOR IMPROVED GAS BARRIER PROPERTIES EASTMAN CHEMICAL COMPANY (US) 2012-08-09 US disclosed
WO-2008140840-A1 CHLORINE RESISTANT POLYAMIDES AND MEMBRANES MADE FROM THE SAME GOVERNMENT OF THE USA AS REPRESENTED BY THE DEPARTMENT OF THE INTERIOR - BUREAU OF RECLAMATION (US) 2008-11-20 WO disclosed
US-20080277333-A1 CHLORINE RESISTANT POLYAMIDES AND MEMBRANES MADE FROM THE SAME SEPARATION SYSTEMS TECHNOLOGY INC. 2008-11-13 US disclosed
US-20080277333-A1 CHLORINE RESISTANT POLYAMIDES AND MEMBRANES MADE FROM THE SAME SEPARATION SYSTEMS TECHNOLOGY INC. 2008-11-13 US disclosed
US-20080277333-A1 CHLORINE RESISTANT POLYAMIDES AND MEMBRANES MADE FROM THE SAME SEPARATION SYSTEMS TECHNOLOGY INC. 2008-11-13 US disclosed
WO-2008031534-A1 INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2008-03-20 WO disclosed
EP-1102743-B1 AMIDE DERIVATIVES WHICH ARE USEFUL AS CYTOKINE INHIBITORS ASTRAZENECA AB (SE) 2002-07-24 EP disclosed
EP-0162663-B1 PROCESS FOR PRODUCING HEAT-RESISTANT MOLDINGS MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1991-08-28 EP disclosed
US-4663375-A THERMOPLASTIC RESIN AND AROMATIC AMIDE MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1987-05-05 US disclosed
US-4568733-A AIRCRAFT THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1986-02-04 US disclosed
US-4142029-A Bis-tetrazoles as chemical blowing agents for foaming thermoplastic resins CIBA-GEIGY CORPORATION (US) 1979-02-27 US disclosed