Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 4/20 | 0.60 |
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.60 |
| ▸ | PARP1 | P09874 | 2/20 | 0.60 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.58 |
| ▸ | GUSB | P08236 | 2/20 | 0.58 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.58 |
| ▸ | MMP2 | P08253 | 4/20 | 0.53 |
| ▸ | MMP9 | P14780 | 4/20 | 0.53 |
| ▸ | MMP8 | P22894 | 4/20 | 0.53 |
| ▸ | MMP13 | P45452 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13828863 | 0.85 | TNKS (0.57) | TNKSTNKS2PARP1PARP2GUSB | |
| SCHEMBL8989109 | 0.80 | TNKS2 (0.57) | TNKSTNKS2PARP1RAB9AKMT2A | |
| SCHEMBL14303513 | 0.77 | ALDH1A1 (0.62) | TNKSTNKS2PARP1PARP2GUSB | |
| SCHEMBL7496014 | 0.77 | POLB (0.72) | TNKSTNKS2PARP1NPC1RAB9A | |
| SCHEMBL13828668 | 0.76 | TNKS (0.56) | TNKSTNKS2PARP1PARP2GUSB | |
| SCHEMBL15775530 | 0.75 | TNKS (1.00) | TNKSTNKS2PARP1PARP2GUSB | |
| SCHEMBL5619043 | 0.74 | TNKS (0.49) | TNKSTNKS2PARP1PARP2GUSB | |
| SCHEMBL15775356 | 0.74 | TNKS (1.00) | TNKSTNKS2PARP1PARP2GUSB | |
| SCHEMBL30665826 | 0.74 | TNKS (0.75) | TNKSTNKS2PARP1PARP2GUSB | |
| SCHEMBL2152867 | 0.73 | TNKS (0.57) | TNKSTNKS2PARP1PARP2GUSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1094929-C | Acetamide derivative, process for preparing the same, and pharmaceutical composition containing the same | DAINIPPON PHARMACEUTICAL CO (JP) | 2002-11-27 | — | — | CN | disclosed |
| EP-0826673-B1 | ACETAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO (JP) | 2002-11-20 | — | — | EP | disclosed |
| US-5972946-A | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1999-10-26 | — | — | US | disclosed |
| CN-1186487-A | Acetamide derivatives, process for producing the same, and medicinal composition containing the same | DAINIPPON PHARMACEUTICAL CO (JP) | 1998-07-01 | — | — | CN | disclosed |
| EP-0826673-A1 | ACETAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1998-03-04 | — | — | EP | disclosed |