Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27257150 | 0.79 | IDO1 (0.33) | IDO1TDO2 | |
| SCHEMBL30491994 | 0.78 | SHBG (0.35) | SHBGIDO1TDO2 | |
| SCHEMBL10887105 | 0.78 | IDO1 (0.33) | IDO1TDO2 | |
| SCHEMBL31482312 | 0.77 | UGT2B7 (0.36) | SHBGIDO1TDO2 | |
| SCHEMBL3389689 | 0.75 | DPP4 (0.35) | — | |
| SCHEMBL28901368 | 0.74 | LMNA (0.31) | — | |
| SCHEMBL30362109 | 0.74 | — | — | |
| SCHEMBL3124099 | 0.74 | — | — | |
| SCHEMBL3118800 | 0.74 | — | — | |
| SCHEMBL4662977 | 0.73 | SHBG (0.31) | SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1158982-A4 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2002-06-12 | — | — | EP | disclosed |
| EP-1158982-A2 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000052134-A2 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2000-09-08 | — | — | WO | disclosed |