Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.72 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.72 |
| ▸ | F2R | P25116 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 4/20 | 0.46 |
| ▸ | BCHE | P06276 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7498550 | 0.96 | ITGB3 (0.69) | ITGB3ITGA2BF2RHTTACHE | |
| SCHEMBL7501816 | 0.94 | ITGB3 (0.63) | ITGB3ITGA2BF2RHTTACHE | |
| SCHEMBL7500193 | 0.94 | ITGB3 (0.65) | ITGB3ITGA2BF2RHTTACHE | |
| SCHEMBL7504164 | 0.92 | ITGB3 (0.74) | ITGB3ITGA2BF2RHTTSMN1; SMN2 | |
| SCHEMBL7446986 | 0.91 | ITGB3 (0.73) | ITGB3ITGA2BF2RHTTSMN1; SMN2 | |
| SCHEMBL7505011 | 0.90 | ITGB3 (0.60) | ITGB3ITGA2BF2RHTTACHE | |
| SCHEMBL7496847 | 0.89 | ITGB3 (0.68) | ITGB3ITGA2BF2RHTTSMN1; SMN2 | |
| SCHEMBL7500186 | 0.88 | ITGB3 (0.59) | ITGB3ITGA2BF2RHTTACHE | |
| SCHEMBL7818397 | 0.88 | ITGB3 (0.59) | ITGB3ITGA2BF2RACHEUSP30 | |
| SCHEMBL7746235 | 0.87 | ITGB3 (0.67) | ITGB3ITGA2BF2RHTTACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380215-B1 | FOR PREVENTION AND/OR TREATMENT OF DISEASES CAUSED BY THROMBUS FORMATION SUCH AS ARTERIAL THROMBOSIS, ARTERIAL SCLEROSIS, ISCHEMIC HEART DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD (JP) | 2002-04-30 | — | — | US | disclosed |
| EP-0669912-B1 | N-(3-PIPERIDINYLCARBONYL)-BETA-ALANINE DERIVATIVES AS PAF ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-12-05 | — | — | EP | disclosed |
| EP-1106606-A2 | N-(3-piperidinylcarbonyl)-beta-alanine derivatives as paf antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-13 | — | — | EP | disclosed |