Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | F2R | P25116 | 8/20 | 0.49 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.46 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.44 |
| ▸ | YAP1 | P46937 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6538573 | 0.94 | ITGB3 (0.54) | ITGB3ITGA2BKDM4EPKMF2R | |
| SCHEMBL7498836 | 0.93 | ITGB3 (0.54) | ITGB3ITGA2BKDM4EPKMF2R | |
| SCHEMBL7440093 | 0.90 | KDM4E (0.56) | ITGB3ITGA2BKDM4EPKMF2R | |
| SCHEMBL7500565 | 0.88 | ITGB3 (0.72) | ITGB3ITGA2BF2RUSP30ACHE | |
| SCHEMBL6936430 | 0.88 | ITGB3 (0.55) | ITGB3ITGA2BF2R | |
| SCHEMBL6937901 | 0.88 | ITGB3 (0.55) | ITGB3ITGA2BF2R | |
| SCHEMBL7452081 | 0.86 | ITGB3 (0.75) | ITGB3ITGA2BF2R | |
| SCHEMBL7503852 | 0.86 | ITGB3 (0.54) | ITGB3ITGA2BKDM4EPKMF2R | |
| SCHEMBL7818399 | 0.85 | ITGB3 (0.55) | ITGB3ITGA2BKDM4EPKMF2R | |
| SCHEMBL7446356 | 0.85 | KDM4E (0.49) | ITGB3ITGA2BKDM4EPKMUSP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0669912-B1 | N-(3-PIPERIDINYLCARBONYL)-BETA-ALANINE DERIVATIVES AS PAF ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-12-05 | — | — | EP | disclosed |
| EP-1106606-A2 | N-(3-piperidinylcarbonyl)-beta-alanine derivatives as paf antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-13 | — | — | EP | disclosed |