Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 11/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GGT1 | P19440 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6535420 | 0.94 | THRA (0.56) | THRATHRBPPARGPPARAPTGS2 | |
| SCHEMBL6535108 | 0.90 | PTGS2 (0.49) | THRATHRBPPARGPPARAPTGS2 | |
| SCHEMBL16065424 | 0.90 | PPARG (0.59) | THRATHRBPPARGPPARAPTGS2 | |
| SCHEMBL11589528 | 0.86 | PTGS2 (0.55) | THRATHRBPPARGPPARAPTGS2 | |
| SCHEMBL1788428 | 0.85 | PPARG (0.62) | THRATHRBPPARGPPARAPTGS2 | |
| SCHEMBL4275191 | 0.85 | PPARG (0.51) | THRATHRBPPARGPPARAPTGS2 | |
| SCHEMBL3873794 | 0.83 | PPARA (0.69) | THRATHRBPPARGPPARAPTGS2 | |
| SCHEMBL10615619 | 0.83 | PTGS2 (0.55) | THRATHRBPPARGPPARAPTGS2 | |
| SCHEMBL3247821 | 0.82 | PTGS2 (0.52) | PPARGPPARAPTGS2KDM4EHSD17B10 | |
| SCHEMBL3043813 | 0.82 | PPARA (0.72) | THRATHRBPPARGPPARAPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1167366-A1 | AMINE DERIVATIVES | Sankyo Company, Limited (JP) | 2002-01-02 | — | — | EP | disclosed |