Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17325625 | 0.82 | ALDH1A1 (0.56) | TSHRKCNN3L3MBTL1POLBKMT2A | |
| SCHEMBL7509435 | 0.81 | MKNK2 (0.52) | ALDH1A1 | |
| SCHEMBL7024590 | 0.77 | APP (0.54) | L3MBTL1HPGD | |
| SCHEMBL6968193 | 0.76 | ALDH1A1 (0.61) | TSHRL3MBTL1POLBKMT2AMEN1 | |
| SCHEMBL25662477 | 0.74 | TSHR (0.57) | TSHRL3MBTL1POLBKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL1646313 | 0.73 | TSHR (0.56) | TSHRL3MBTL1POLBKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL30409330 | 0.73 | TSHR (0.56) | TSHRL3MBTL1POLBKMT2AMEN1 | |
| SCHEMBL6960534 | 0.73 | ALDH1A1 (0.62) | TSHRPOLBKMT2AMEN1ALDH1A1 | |
| SCHEMBL24298639 | 0.72 | ALDH1A1 (0.60) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL15265345 | 0.72 | L3MBTL1 (0.62) | TSHRL3MBTL1POLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1206265-A4 | SRC KINASE INHIBITOR COMPOUNDS | MERCK & CO INC (US) | 2002-08-07 | — | — | EP | disclosed |
| EP-1206265-A1 | SRC KINASE INHIBITOR COMPOUNDS | Merck & Co., Inc. (US) | 2002-05-22 | — | — | EP | disclosed |
| WO-2001000213-A1 | SRC KINASE INHIBITOR COMPOUNDS | MERCK & CO., INC. (US) | 2001-01-04 | — | — | WO | disclosed |