Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7506697 | 0.89 | MEN1 (0.40) | HSD17B2ALDH1A1TSHRMAPK1KDM4E | |
| SCHEMBL7508169 | 0.86 | CHRNA1 (0.49) | ALDH1A1TSHRPOLBLMNAMEN1 | |
| SCHEMBL7502271 | 0.82 | MAPT (0.46) | LMNAMEN1KMT2AMAPTSLC6A4 | |
| SCHEMBL13724641 | 0.78 | HDAC3 (0.50) | ALDH1A1LMNAL3MBTL1SLC6A4 | |
| SCHEMBL6184304 | 0.78 | HSD17B2 (0.40) | HSD17B2ALDH1A1TSHRPOLBCYP2C19 | |
| SCHEMBL2901704 | 0.77 | ALDH1A1 (0.37) | HSD17B2ALDH1A1TSHRPOLBMAPK1 | |
| SCHEMBL10830983 | 0.77 | CES2 (0.47) | ALDH1A1TSHRL3MBTL1MEN1KMT2A | |
| SCHEMBL10628840 | 0.75 | HDAC1 (0.47) | ALDH1A1TSHRPOLBKDM4ELMNA | |
| SCHEMBL10516761 | 0.74 | CA12 (0.34) | ALDH1A1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL20350872 | 0.74 | KDM4E (0.49) | ALDH1A1KDM4EL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882725-B1 | QUINOLONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2002-12-18 | — | — | EP | disclosed |
| US-6025370-A | METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS | TOYAMA CHEMICAL CO., LTD. (JP) | 2000-02-15 | — | — | US | disclosed |
| EP-0882725-A1 | QUINOLONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 1998-12-09 | — | — | EP | disclosed |