Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GBA1 | P04062 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2577341 | 0.79 | MEN1 (0.54) | MEN1KMT2AMAPTATMCYP1A2 | |
| SCHEMBL7497628 | 0.79 | GAA (0.45) | RXRACYP1A2CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL7506752 | 0.77 | GAA (0.44) | CYP1A2CYP2C9CYP2C19L3MBTL1NPC1 | |
| SCHEMBL7507122 | 0.77 | KCNH2 (0.48) | RXRAMAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7505001 | 0.76 | MEN1 (0.53) | RXRAMEN1KMT2ACYP1A2NPC1 | |
| SCHEMBL13603916 | 0.76 | MEN1 (0.54) | MEN1KMT2AMAPTATMCYP1A2 | |
| SCHEMBL9013611 | 0.74 | MAPT (0.54) | MEN1KMT2AMAPTATMCYP1A2 | |
| Propane SCHEMBL10850974 | 0.73 | MEN1 (0.52) | MEN1KMT2AMAPTATMCYP1A2 | |
| Hydrochloric Acid SCHEMBL9013362 | 0.73 | MAPT (0.52) | MEN1KMT2AMAPTATMCYP1A2 | |
| Hydrochloric Acid SCHEMBL9013331 | 0.72 | HTR6 (0.60) | MEN1KMT2AMAPTATMCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826673-B1 | ACETAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO (JP) | 2002-11-20 | — | — | EP | disclosed |
| US-5972946-A | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0826673-A1 | ACETAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1998-03-04 | — | — | EP | disclosed |