Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9013362 | 0.99 | MAPT (0.52) | MAPTATMMEN1CYP1A2CYP2C9 | |
| Hydrochloric Acid SCHEMBL9013331 | 0.85 | HTR6 (0.60) | MAPTATMMEN1CYP1A2CYP2C9 | |
| Hydrochloric Acid SCHEMBL9013688 | 0.85 | ESR1 (0.62) | — | |
| Hydrochloric Acid SCHEMBL9013838 | 0.77 | TP53 (0.54) | CYP1A2CYP2C9MAPK1CYP2C19ALDH1A1 | |
| SCHEMBL7273983 | 0.77 | MEN1 (0.55) | MAPTATMMEN1CYP1A2CYP2C9 | |
| SCHEMBL6605589 | 0.76 | HTR6 (0.56) | MAPTATMALDH1A1LMNAHTT | |
| SCHEMBL11580118 | 0.76 | HTR7 (0.54) | MAPTMEN1CYP1A2CYP2C9HPGD | |
| SCHEMBL7500942 | 0.74 | RXRA (0.50) | MAPTATMMEN1CYP1A2CYP2C9 | |
| SCHEMBL13603916 | 0.73 | MEN1 (0.54) | MAPTATMMEN1CYP1A2CYP2C9 | |
| Hydrochloric Acid SCHEMBL9013623 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5589477-A | LEARNING ENHANCEMENT, CNS | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1996-12-31 | — | — | US | claimed |