SCHEMBL750097

SCHEMBL750097

CCC(C(=O)O)c1cccc(N)c1

nearest known ligand 0.71

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CPN1 P15169 2/20 0.71
CPB2 Q96IY4 2/20 0.71
AKR1C3 P42330 12/20 0.49
AKR1C2 P52895 12/20 0.49
AKR1C1 Q04828 1/20 0.49
PTGS1 P23219 1/20 0.49
PBRM1 Q86U86 1/20 0.44
LMNA P02545 2/20 0.41
HSD17B10 Q99714 1/20 0.41
ALDH1A1 P00352 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23566793 0.87 CPN1 (0.67) CPN1CPB2AKR1C3AKR1C2AKR1C1
SCHEMBL6550969 0.84 CPN1 (0.68) CPN1CPB2ALDH1A1MEN1KMT2A
SCHEMBL2352530 0.83 CPN1 (1.00) CPN1CPB2PBRM1LMNAMEN1
SCHEMBL31478057 0.82 CPN1 (0.53) CPN1CPB2LMNAMEN1KMT2A
SCHEMBL2079660 0.82 CPN1 (0.49) CPN1CPB2AKR1C3AKR1C2AKR1C1
SCHEMBL28032981 0.82 AKR1C3 (0.46) CPN1CPB2AKR1C3AKR1C2AKR1C1
SCHEMBL1801772 0.81 AKR1C3 (0.52) CPN1CPB2AKR1C3AKR1C2AKR1C1
SCHEMBL1820061 0.81 KYNU (0.51) CPN1CPB2AKR1C3AKR1C2AKR1C1
SCHEMBL1653534 0.81 AKR1C3 (0.52) CPN1CPB2AKR1C3AKR1C2AKR1C1
SCHEMBL29687004 0.81 KYNU (0.51) CPN1CPB2AKR1C3AKR1C2AKR1C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3059004-B1 METHOD FOR REMOVING SOX FROM GAS WITH COMPLEX ALCOHOL-AMINE SOLUTION BEIJING BOYUAN HENGSHENG HIGH TECH CO LTD (CN) 2021-06-30 EP claimed
US-9999852-B2 Method for removing SOx from gas with compound alcohol-amine solution BEIJING BOYUAN HENGSHENG HIGH-TECHNOLOGY CO., LTD (CN) 2018-06-19 US claimed
US-20160243491-A1 Method for Removing SOx from Gas with Compound Alcohol-Amine Solution PEKING UNIVERSITY (CN) 2016-08-25 US claimed
EP-3059004-A1 METHOD FOR REMOVING SOX FROM GAS WITHNCOMPOUND ALCOHOL-AMINE SOLUTION Beijing Boyuan-Hengsheng High-Technology Co., Ltd. (CN) 2016-08-24 EP claimed
CN-103495340-B The method of SOx in compound alcamines solution removal gas BEIJING BOYUAN HENGSHENG HIGH-TECHNOLOGY CO.,LTD. (CN) 2015-11-18 CN claimed
CN-103495340-A Method of removing SOx in gas by compound alkanolamine solution BEIJING BOYUAN HENGSHENG HIGH TECHNOLOGY CO LTD 2014-01-08 CN claimed
CN-119930496-A Preparation method of 2- [4- (1-oxo-2-isoindolinyl) phenyl ] butyric acid 山东诚成医药科技有限公司 2025-05-06 CN disclosed
CN-119395197-A Detection method of genotoxic impurity o-methylbenzaldehyde in indobufen 湖南方盛制药股份有限公司 2025-02-07 CN disclosed
CN-116297908-B Analysis method of indobufen isomer impurity 湖南九典制药股份有限公司 2024-06-14 CN disclosed
CN-116297908-A Analysis method of indobufen isomer impurity 湖南九典制药股份有限公司 2023-06-23 CN disclosed
EP-3059004-B1 METHOD FOR REMOVING SOX FROM GAS WITH COMPLEX ALCOHOL-AMINE SOLUTION BEIJING BOYUAN HENGSHENG HIGH TECH CO LTD (CN) 2021-06-30 EP disclosed
US-9999852-B2 Method for removing SOx from gas with compound alcohol-amine solution BEIJING BOYUAN HENGSHENG HIGH-TECHNOLOGY CO., LTD (CN) 2018-06-19 US disclosed
US-20160243491-A1 Method for Removing SOx from Gas with Compound Alcohol-Amine Solution PEKING UNIVERSITY (CN) 2016-08-25 US disclosed
CN-103495340-B The method of SOx in compound alcamines solution removal gas BEIJING BOYUAN HENGSHENG HIGH-TECHNOLOGY CO.,LTD. (CN) 2015-11-18 CN disclosed
CN-103495340-A Method of removing SOx in gas by compound alkanolamine solution BEIJING BOYUAN HENGSHENG HIGH TECHNOLOGY CO LTD 2014-01-08 CN disclosed
US-8163756-B2 For example,1-(3-t-butyl-1- (1,2,3,4-tetrahydro- isoquinolin-6-yl)-1H- pyrazol-5-yl)-3-(3- cyanophenyl)urea; for treatment of mammalian cancers and inflammatory diseases including rheumatoid arthritis, retinopathies DECIPHERA PHARMACEUTICALS, LLC (US) 2012-04-24 US disclosed
EP-1996563-B1 HETEROBICYCLIC SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF DIABETES HOFFMANN LA ROCHE (CH) 2012-03-21 EP disclosed
US-8030308-B2 Bicyclic sulfonamide derivatives which are L-CPT 1 inhibitors HOFFMANN-LA ROCHE INC. (US) 2011-10-04 US disclosed
US-20110046112-A1 NOVEL BICYCLIC SULFONAMIDE DERIVATIVES WHICH ARE L-CPT1 INHIBITORS ACKERMANN JEAN 2011-02-24 US disclosed
US-7879845-B2 Liver carnitine-dependent palmitoyltransferase (L-CPT1) inhibitors such as 4-{[4-(5-Chloro-2-methoxy-benzenesulfonyl)-3,4-dihydro-2H-benzo[1,4]thiazine-6-carbonyl]-amino}-benzoic acid, used for the treatment of non-insulin dependent diabetes; antidiabetic agents HOFFMANN-LA ROCHE INC. (US) 2011-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110046112-A1 NOVEL BICYCLIC SULFONAMIDE DERIVATIVES WHICH ARE L-CPT1 INHIBITORS CPT1A, CPT1B, CPT2 CPN1 830/4885CPB2 2211/4885AKR1C3 466/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.