Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 6/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | KRAS | P01116 | 1/20 | 0.41 |
| ▸ | TLK2 | Q86UE8 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7501096 | 1.00 | CYP1A2 (0.48) | CYP1A2CYP2D6CYP1A1AURKAABCG2 | |
| SCHEMBL7499540 | 0.92 | AURKA (0.56) | CYP1A2CYP2D6CYP1A1AURKAABCG2 | |
| SCHEMBL7499548 | 0.92 | AURKA (0.56) | CYP1A2CYP2D6CYP1A1AURKAABCG2 | |
| SCHEMBL7501712 | 0.85 | ABCG2 (0.59) | CYP1A2CYP2D6CYP1A1ABCG2CYP1B1 | |
| SCHEMBL7501717 | 0.85 | ABCG2 (0.59) | CYP1A2CYP2D6CYP1A1ABCG2CYP1B1 | |
| SCHEMBL20518159 | 0.79 | ABCG2 (0.60) | CYP1A2CYP2D6CYP1A1ABCG2CYP1B1 | |
| SCHEMBL7507526 | 0.78 | ABCG2 (0.61) | CYP1A2CYP2D6CYP1A1ABCG2CYP1B1 | |
| SCHEMBL7507534 | 0.78 | ABCG2 (0.61) | CYP1A2CYP2D6CYP1A1ABCG2CYP1B1 | |
| SCHEMBL7502109 | 0.77 | ABCG2 (0.62) | CYP1A2CYP2D6CYP1A1ABCG2CYP1B1 | |
| SCHEMBL7495859 | 0.77 | ABCG2 (0.62) | ABCG2TNFRSF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0924202-B1 | Imidazole derivative and medicine comprising the same as active ingredient | SSP CO LTD (JP) | 2002-05-29 | — | — | EP | disclosed |
| US-6071943-A | IMMUNOMODULATORS WHICH SUPPRESS SPECIFIC CYTOKINES, FOR AUTOIMMUNE DISEASES | SSP CO. LTD. (JP) | 2000-06-06 | — | — | US | disclosed |
| EP-0924202-A1 | Imidazole derivative and medicine comprising the same as active ingredient | SSP Co., Ltd. (JP) | 1999-06-23 | — | — | EP | disclosed |