Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 5/20 | 0.50 |
| ▸ | MAOA | P21397 | 4/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.44 |
| ▸ | RELA | Q04206 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7499548 | 1.00 | AURKA (0.56) | AURKACYP3A4MAOBMAOAABCG2 | |
| SCHEMBL7501096 | 0.92 | CYP1A2 (0.48) | AURKACYP3A4MAOBMAOAABCG2 | |
| SCHEMBL7501089 | 0.92 | CYP1A2 (0.48) | AURKACYP3A4MAOBMAOAABCG2 | |
| SCHEMBL7501712 | 0.81 | ABCG2 (0.59) | CYP3A4MAOBABCG2CYP1A1CYP1A2 | |
| SCHEMBL7501717 | 0.81 | ABCG2 (0.59) | CYP3A4MAOBABCG2CYP1A1CYP1A2 | |
| SCHEMBL20518106 | 0.78 | ABCG2 (0.57) | ABCG2 | |
| SCHEMBL19880069 | 0.77 | AURKA (0.82) | AURKACYP3A4MAOBMAOAABCG2 | |
| SCHEMBL20518159 | 0.75 | ABCG2 (0.60) | CYP3A4ABCG2CYP1A1CYP1A2CYP2D6 | |
| SCHEMBL25193904 | 0.75 | MAPT (0.71) | AURKACYP3A4MAOBMAOAABCG2 | |
| SCHEMBL7502155 | 0.75 | HSP90AA1 (0.60) | CYP3A4MAOBMAOAABCG2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0924202-B1 | Imidazole derivative and medicine comprising the same as active ingredient | SSP CO LTD (JP) | 2002-05-29 | — | — | EP | disclosed |
| US-6071943-A | IMMUNOMODULATORS WHICH SUPPRESS SPECIFIC CYTOKINES, FOR AUTOIMMUNE DISEASES | SSP CO. LTD. (JP) | 2000-06-06 | — | — | US | disclosed |
| EP-0924202-A1 | Imidazole derivative and medicine comprising the same as active ingredient | SSP Co., Ltd. (JP) | 1999-06-23 | — | — | EP | disclosed |