Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.59 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TLK2 | Q86UE8 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 2/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.46 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7501712 | 1.00 | ABCG2 (0.59) | ABCG2ABCB1MAOBCYP3A4TLK2 | |
| SCHEMBL7502412 | 0.87 | AR (0.44) | ABCG2MAOBARMEN1MAPT | |
| SCHEMBL7502417 | 0.87 | AR (0.44) | ABCG2MAOBARMEN1MAPT | |
| SCHEMBL7501089 | 0.85 | CYP1A2 (0.48) | ABCG2MAOBCYP3A4TLK2CYP1A1 | |
| SCHEMBL7501096 | 0.85 | CYP1A2 (0.48) | ABCG2MAOBCYP3A4TLK2CYP1A1 | |
| SCHEMBL7495859 | 0.84 | ABCG2 (0.62) | ABCG2MAPT | |
| SCHEMBL7502109 | 0.84 | ABCG2 (0.62) | ABCG2CYP3A4CYP1A1CYP1A2CYP2D6 | |
| SCHEMBL7502106 | 0.84 | ABCG2 (0.62) | ABCG2CYP3A4CYP1A1CYP1A2CYP2D6 | |
| SCHEMBL7495868 | 0.84 | ABCG2 (0.62) | ABCG2MAPT | |
| SCHEMBL7501148 | 0.82 | GPR52 (0.43) | ABCG2ABCB1TLK2GPR52MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0924202-B1 | Imidazole derivative and medicine comprising the same as active ingredient | SSP CO LTD (JP) | 2002-05-29 | — | — | EP | disclosed |
| US-6071943-A | IMMUNOMODULATORS WHICH SUPPRESS SPECIFIC CYTOKINES, FOR AUTOIMMUNE DISEASES | SSP CO. LTD. (JP) | 2000-06-06 | — | — | US | disclosed |
| EP-0924202-A1 | Imidazole derivative and medicine comprising the same as active ingredient | SSP Co., Ltd. (JP) | 1999-06-23 | — | — | EP | disclosed |