Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.59 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7235702 | 0.98 | ABCB1 (0.58) | ABCB1ABCG2MEN1KMT2ANPC1 | |
| SCHEMBL13917946 | 0.87 | ABCB1 (0.62) | ABCB1ABCG2MEN1KMT2ANPC1 | |
| SCHEMBL3712764 | 0.86 | MEN1 (0.60) | ABCB1ABCG2MEN1KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL42327 | 0.84 | MEN1 (0.59) | ABCB1ABCG2MEN1KMT2ANPC1 | |
| SCHEMBL5653057 | 0.84 | NPC1 (0.64) | ABCB1ABCG2MEN1KMT2ANPC1 | |
| SCHEMBL12963323 | 0.83 | ABCB1 (0.73) | ABCB1ABCG2MEN1KMT2ANPC1 | |
| SCHEMBL67744 | 0.83 | KDM4E (0.68) | ABCB1ABCG2MEN1KMT2AKDM4E | |
| SCHEMBL8306114 | 0.83 | KDM4E (0.64) | ABCB1ABCG2MEN1KMT2ANPC1 | |
| SCHEMBL30028263 | 0.83 | KDM4E (0.68) | ABCB1ABCG2MEN1KMT2AKDM4E | |
| SCHEMBL11008456 | 0.83 | CA2 (0.63) | ABCB1KMT2AKDM4ECYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1390834-A | Indenoindolone compounds, their preparation and medicinal compositions containing them | SEUVILE LAB (FR) | 2003-01-15 | — | — | CN | disclosed |
| EP-1266887-A2 | Indenoindoline derivatives, their process of preparation and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2002-12-18 | — | — | EP | disclosed |