Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 7/20 | 0.69 |
| ▸ | CHRNA4 | P43681 | 7/20 | 0.69 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.69 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7495819 | 0.82 | CHRNB2 (0.69) | CHRNB2CHRNA4CHRNA1CHRNA7KMT2A | |
| SCHEMBL7504331 | 0.82 | CHRNB2 (1.00) | CHRNB2CHRNA4CHRNA1CHRNA7KMT2A | |
| SCHEMBL7504394 | 0.74 | CHRNB2 (0.58) | CHRNB2CHRNA4CHRNA1CHRNA7KMT2A | |
| SCHEMBL7501821 | 0.74 | CHRNB2 (0.67) | CHRNB2CHRNA4CHRNA1CHRNA7KMT2A | |
| SCHEMBL7506033 | 0.72 | CHRNB2 (0.60) | CHRNB2CHRNA4CHRNA1CHRNA7KMT2A | |
| SCHEMBL23749741 | 0.72 | CHRNB2 (0.59) | CHRNB2CHRNA4CHRNA1CHRNA7KMT2A | |
| SCHEMBL7503621 | 0.71 | CYP11B1 (0.41) | CHRNB2CHRNA4CHRNA1CHRNA7KMT2A | |
| SCHEMBL7498533 | 0.69 | CHRNB2 (0.60) | CHRNB2CHRNA4CHRNA1CHRNA7KMT2A | |
| SCHEMBL7506101 | 0.69 | CHRNB2 (0.56) | CHRNB2CHRNA4CHRNA1CHRNA7KMT2A | |
| SCHEMBL1273680 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020028809-A1 | Heterocyclic compounds having effect of activating a4beta2 nicotinic acetylcholine receptors | SUNTORY LIMITED | 2002-03-07 | — | — | US | disclosed |
| EP-1176141-A1 | HETEROCYCLIC COMPOUNDS HAVING EFFECT OF ACTIVATING NICOTINIC ACETYLCHOLINE $g(a)4$g(b)2 RECEPTOR | SUNTORY LIMITED (JP) | 2002-01-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020028809-A1 | Heterocyclic compounds having effect of activating a4beta2 nicotinic acetylcholine receptors | CHRNA2, CHRNA7, CHRNB2 | CHRNB2 3/4885CHRNA4 8/4885CHRNA1 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.