SCHEMBL465794

SCHEMBL465794

NC(CC(=O)O)C(N)(CC(=O)O)CC(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.40
SLC22A6 Q4U2R8 1/20 0.36
GABRR1 P24046 2/20 0.36
LMNA P02545 1/20 0.36
KDM4E B2RXH2 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HMGCR P04035 1/20 0.33
CHRM1 P11229 1/20 0.33
TBXA2R P21731 1/20 0.33
ADRA1A P35348 1/20 0.33
CYP2D6 P10635 1/20 0.32
TSHR P16473 1/20 0.32
CYP2C19 P33261 1/20 0.32
HIF1A Q16665 1/20 0.32
CPT2 P23786 1/20 0.31
ACLY P53396 1/20 0.31
CACNB3 P54284 1/20 0.30
CACNA2D1 P54289 1/20 0.30
CACNA1C Q13936 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adipic Acid SCHEMBL1026036 0.84 LMNA (0.50) SLC22A6GABRR1LMNAALDH1A1CYP2D6
SCHEMBL750130 0.78 TDP1 (0.42) TDP1SLC22A6GABRR1LMNAKDM4E
SCHEMBL5690732 0.77 TDP1 (0.37) TDP1SLC22A6GABRR1LMNAKDM4E
SCHEMBL396503 0.76 TDP1 (0.40) TDP1SLC22A6GABRR1LMNAKDM4E
SCHEMBL7999396 0.76 TDP1 (0.40) TDP1SLC22A6GABRR1LMNAKDM4E
SCHEMBL8976857 0.76 TDP1 (0.36) TDP1SLC22A6GABRR1LMNAKDM4E
SCHEMBL28726922 0.76 SLC22A6 (0.37) TDP1SLC22A6GABRR1LMNAKDM4E
SCHEMBL5690770 0.74 HMGCR (0.38) TDP1SLC22A6GABRR1LMNAALDH1A1
SCHEMBL5692405 0.73 HMGCR (0.37) TDP1SLC22A6GABRR1LMNAKDM4E
Ammonia Solution, Strong SCHEMBL10590157 0.73 TDP1 (0.38) TDP1SLC22A6GABRR1LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 553 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3986465-B1 SITE-SPECIFIC, KINETICALLY INERT CONJUGATION OF LABELS AND/OR CARRIERS TO TARGET MOLECULES SUCH AS HIS-TAGGED PROTEINS VIA METAL COMPLEX REAGENTS MAX PLANCK GESELLSCHAFT (DE) 2026-05-13 EP claimed
US-12497422-B2 Site-specific, kinetically inert conjugation of labels and/or carriers to target molecules such as His-tagged proteins via metal complex reagents Max-Planck-Gesellschaft zur Förderung der Wissenschaften e. V. (DE) 2025-12-16 US claimed
WO-2025042580-A2 WOOD MICROFLUIDIC ENGINEERING: DEVELOPMENT OF HIGHLY STABLE POLYMER NANOCOMPOSITE ELECTROCHEMICAL NITRATE SENSOR UNIVERSITY OF MARYLAND, BALTIMORE COUNTY (US) 2025-02-27 WO claimed
EP-4480500-A1 MODIFIED CELL, PHARMACEUTICAL COMPOSITION AND METHOD OF PREPARING A MODIFIED CELL Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2024-12-25 EP claimed
CN-118179451-A Metal chelate chromatography medium and preparation method and application thereof 中国科学院过程工程研究所 2024-06-14 CN claimed
CN-117836401-A Commercial purification method of high purity bacterial extracellular vesicles 罗塞塔外排体株式会社 2024-04-05 CN claimed
CN-117377521-A Synthetic polymeric porous media with hierarchical multi-layer structure and design, synthesis, modification and liquid chromatography applications thereof 苏州赛分科技股份有限公司 2024-01-09 CN claimed
EP-4291542-A1 METHOD OF PRODUCING A SHAPED CERAMIC BODY, IN PARTICULAR A DENTAL SHAPED CERAMIC BODY Pritidenta GmbH (DE) 2023-12-20 EP claimed
WO-2022270872-A1 COMMERCIAL PURIFICATION METHOD FOR HIGH-PURITY BACTERIAL EXTRACELLULAR VESICLES (주)로제타엑소좀 2022-12-29 WO claimed
US-20220389053-A1 PURIFICATION PROCESS BASED ON MAGNETIC BEADS LAB-ON-A-BEAD AB (SE) 2022-12-08 US claimed
EP-1363714-A1 A MICROCHIP ELECTROSPRAY DEVICE AND COLUMN WITH AFFINITY ADSORBENTS AND USE OF THE SAME Advion BioSciences, Inc. (US) 2003-11-26 EP claimed
US-20020139751-A1 Microchip electrospray device and column with affinity adsorbents and use of the same ADVION BIOSCIENCES, INC. 2002-10-03 US claimed
WO-2002066135-A1 A MICROCHIP ELECTROSPRAY DEVICE AND COLUMN WITH AFFINITY ADSORBENTS AND USE OF THE SAME ADVION BIOSCIENCES, INC. (US) 2002-08-29 WO claimed
US-6365147-B1 BINDING, ACCUMULATION NEW JERSEY INSTITUTE OF TECHNOLOGY 2002-04-02 US claimed
EP-0812200-B1 PROTEIN PURIFICATION AVANT IMMUNOTHERAPEUTICS INC (US) 2002-02-27 EP claimed
WO-2000041721-A1 PROCESS FOR PURIFYING IMMUNOGLOBULINS CSL LIMITED (AU) 2000-07-20 WO claimed
WO-1999066333-A1 NEUTRAL ENHANCEMENT OF LANTHANIDES FOR TIME RESOLVED FLUORESCENCE NEN LIFE SCIENCE PRODUCTS, INC. (US) 1999-12-23 WO claimed
US-5840858-A Protein purification using immobilized metal affinity chromatography for complement receptor proteins T CELL SCIENCES, INC. (US) 1998-11-24 US claimed
US-5409677-A Process for separating a radionuclide from solution THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 1995-04-25 US claimed
WO-1994015950-A1 PURIFICATION OF IMMUNOGLOBULIN THE WELLCOME FOUNDATION LIMITED (GB) 1994-07-21 WO claimed