Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15684403 | 0.85 | MAPT (0.58) | MAPTPKM | |
| SCHEMBL17756105 | 0.85 | MAPT (0.58) | MAPTPKM | |
| SCHEMBL8436600 | 0.82 | CHRNB2 (0.32) | — | |
| SCHEMBL23152247 | 0.80 | MAPT (0.32) | MAPTPKM | |
| SCHEMBL3093516 | 0.80 | MAPT (0.34) | MAPTPKMKMT2ACYP2D6 | |
| SCHEMBL167002 | 0.79 | SSTR4 (0.34) | MAPTPKMKMT2ACYP2D6 | |
| SCHEMBL19973194 | 0.78 | MAPT (0.33) | MAPTPKM | |
| SCHEMBL1555124 | 0.77 | GABRR1 (0.35) | — | |
| SCHEMBL661356 | 0.76 | MAPT (0.38) | MAPTPKMTSHRKMT2ACYP2D6 | |
| SCHEMBL659836 | 0.76 | MAPT (0.38) | MAPTPKMTSHRKMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202987-A2 | QUINOLINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 2002-05-08 | — | — | EP | disclosed |
| WO-2001007433-A2 | QUINOLINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-02-01 | — | — | WO | disclosed |