Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4496862 | 0.78 | DRD2 (0.56) | DRD2DRD4ALDH1A1MAPTAR | |
| SCHEMBL6582387 | 0.72 | DRD2 (0.50) | DRD2DRD4ALDH1A1MAPTAR | |
| SCHEMBL4504545 | 0.69 | DRD2 (0.47) | DRD2DRD4ALDH1A1MAPTAR | |
| SCHEMBL21678125 | 0.66 | — | — | |
| SCHEMBL13154646 | 0.65 | DRD2 (0.44) | DRD2DRD4ALDH1A1MAPTAR | |
| SCHEMBL2265794 | 0.64 | DRD2 (0.47) | DRD2DRD4ALDH1A1MAPTAR | |
| SCHEMBL93915 | 0.64 | DRD2 (0.57) | DRD2DRD4ALDH1A1MAPTAR | |
| SCHEMBL29358285 | 0.64 | DRD2 (0.57) | DRD2DRD4ALDH1A1MAPTAR | |
| SCHEMBL8261456 | 0.64 | DRD2 (0.47) | DRD2DRD4ALDH1A1MAPTAR | |
| SCHEMBL8529795 | 0.64 | DRD2 (0.52) | DRD2DRD4ALDH1A1MAPTAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888349-B1 | PYRROLOPYRIMIDINES AND PROCESSES FOR THEIR PREPARATION | NOVARTIS AG (CH) | 2002-05-22 | — | — | EP | claimed |
| US-6140317-A | AS INHIBITORS OF PROTEIN KINASES AND HAVE ANTITUMOUR ACTIVITY | NOVARTIS AG (CH) | 2000-10-31 | — | — | US | claimed |
| EP-0888349-B1 | PYRROLOPYRIMIDINES AND PROCESSES FOR THEIR PREPARATION | NOVARTIS AG (CH) | 2002-05-22 | — | — | EP | disclosed |
| US-6140317-A | AS INHIBITORS OF PROTEIN KINASES AND HAVE ANTITUMOUR ACTIVITY | NOVARTIS AG (CH) | 2000-10-31 | — | — | US | disclosed |