Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | NNMT | P40261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10844992 | 0.98 | DRD2 (0.45) | DRD2DRD4MAPTALDH1A1AR | |
| SCHEMBL13946269 | 0.83 | ALDH1A1 (0.53) | DRD2DRD4MAPTALDH1A1AR | |
| SCHEMBL4496862 | 0.82 | DRD2 (0.56) | DRD2DRD4MAPTALDH1A1AR | |
| SCHEMBL13942395 | 0.80 | HTR2A (0.43) | DRD2DRD4MAPTALDH1A1MEN1 | |
| SCHEMBL13244147 | 0.78 | SMN1; SMN2 (0.41) | DRD2DRD4MAPTALDH1A1AR | |
| SCHEMBL2267850 | 0.76 | MAPT (0.67) | DRD2DRD4MAPTALDH1A1MEN1 | |
| SCHEMBL6582387 | 0.75 | DRD2 (0.50) | DRD2DRD4MAPTALDH1A1AR | |
| Hydrochloric Acid SCHEMBL10848491 | 0.74 | MAPT (0.65) | DRD2DRD4MAPTALDH1A1MEN1 | |
| SCHEMBL1880170 | 0.73 | DRD2 (0.59) | DRD2DRD4MAPTALDH1A1CA12 | |
| SCHEMBL29642933 | 0.73 | DRD2 (0.59) | DRD2DRD4MAPTALDH1A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040231067-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and heterocyclic coupler, methods and uses | L'OREAL (FR) | 2004-11-25 | — | — | US | claimed |
| EP-0575604-B2 | INDOLINE PRODUCTS, METHODS FOR PREPARING SAME, AND USE THEREOF IN COSMETICS | OREAL (FR) | 2003-03-26 | — | — | EP | claimed |
| US-5776497-A | OXIDATIVE POLYMERIZATION OF INDOLINE FOR COSMETICS | L'OREAL (FR) | 1998-07-07 | — | — | US | claimed |
| EP-0544874-B1 | METHOD FOR PREPARING SUBMICRON PARTICLES IN THE PRESENCE OF LIPID VESICLES, AND CORRESPONDING COMPOSITIONS | OREAL (FR) | 1998-04-08 | — | — | EP | claimed |
| US-5670099-A | PREPARING A DISPERSION OF LIPIDIC VESICLES FROM ATLEAST ONE LIPID, AN AQUEOUS PHASE ENCAPSULATED IN VESICLE, DISSOLVING POLYMERIZABLE INDOLIC OR INDOLINIC MONOMER WITH A POLYMERIZATION AGENT, REACTS WITH MONOMER FORMS PARTICLES | L'OREAL (FR) | 1997-09-23 | — | — | US | claimed |
| US-5583234-A | Indoline-based products, processes for preparing them and their use in cosmetics | L'OREAL (FR) | 1996-12-10 | — | — | US | claimed |
| EP-0575605-B1 | MINERAL OR ORGANIC PARTICLE BASED PRODUCT COMPRISING AN INDOLINE PRODUCT | OREAL (FR) | 1996-11-27 | — | — | EP | claimed |
| US-5496543-A | COSMETICS | L'OREAL (FR) | 1996-03-05 | — | — | US | claimed |
| EP-0575604-B1 | INDOLINE PRODUCTS, METHODS FOR PREPARING SAME, AND USE THEREOF IN COSMETICS | OREAL (FR) | 1995-12-06 | — | — | EP | claimed |
| EP-0575604-A1 | INDOLINE PRODUCTS, METHODS FOR PREPARING SAME, AND USE THEREOF IN COSMETICS. | OREAL (FR) | 1993-12-29 | — | — | EP | claimed |
| EP-0575605-A1 | MINERAL OR ORGANIC PARTICLE BASED PRODUCT COMPRISING AN INDOLINE PRODUCT. | OREAL (FR) | 1993-12-29 | — | — | EP | claimed |
| WO-1993013744-A1 | INDOLINE PRODUCTS, METHODS FOR PREPARING SAME, AND USE THEREOF IN COSMETICS | L'OREAL (FR) | 1993-07-22 | — | — | WO | claimed |
| WO-1993013745-A1 | MINERAL OR ORGANIC PARTICLE BASED PRODUCT COMPRISING AN INDOLINE PRODUCT | L'OREAL (FR) | 1993-07-22 | — | — | WO | claimed |
| US-4013404-A | Method of dyeing hair with indolines, indoles and indazoles | AMERICAN CYANAMID COMPANY (US) | 1977-03-22 | — | — | US | claimed |
| EP-2182914-B1 | COMPOSITION OXIDATION COLOURING OF KERATINIC FIBRES, CONTAINING A CATIONIC CELLULOSE ETHER, A METASILICATE AND OXIDATION DYES, METHOD FOR OXIDATION COLOURING AND USES THEREOF | L'ORÉAL (FR) | 2017-11-08 | — | — | EP | disclosed |
| EP-2175830-B1 | COMPOSITION FOR OXIDATION DYEING KERATIN FIBRES COMPRISING A CATIONIC CELLULOSE ETHER, A WEAKLY OXYETHYLENATED SORBITAN FATTY ACID ESTER AND OXIDATION DYES | ORÉAL L (FR) | 2015-09-30 | — | — | EP | disclosed |
| US-8043385-B2 | Composition oxidation colouring of keratinic fibres, containing a cationic cellulose ether, a metasilicate and oxidation dyes, method for oxidation colouring and uses thereof | L'OREAL S.A. (FR) | 2011-10-25 | — | — | US | disclosed |
| EP-0544874-A1 | METHOD FOR PREPARING SUBMICRON PARTICLES IN THE PRESENCE OF LIPID VESICLES, AND CORRESPONDING COMPOSITIONS | L'OREAL (FR) | 1993-06-09 | — | — | EP | disclosed |
| WO-1993000068-A1 | METHOD FOR PREPARING SUBMICRON PARTICLES IN THE PRESENCE OF LIPID VESICLES, AND CORRESPONDING COMPOSITIONS | L'OREAL (FR) | 1993-01-07 | — | — | WO | disclosed |
| US-4013404-A | Method of dyeing hair with indolines, indoles and indazoles | AMERICAN CYANAMID COMPANY (US) | 1977-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040231067-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and heterocyclic coupler, methods and uses | KRT18, CDC73, PYCR1 | DRD2 611/4885DRD4 537/4885MAPT 1406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.